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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: ECHELON BIOSCIENCES, INC.            Topic: CBD192007

    Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: Technology Holding, LLC            Topic: CBD192007

    The threat of organophosphate (OP) chemical warfare agents (CWA) to United States military personnel is a persistent problem due to the relative ease of manufacturing chemical threats compared to nuclear and biological agents. Human butyrylcholinesterase (BChE) has been identified as a probable bio-scavenger of OP CWAs that could be used to protect individuals that could be exposed to OP CWAs. The ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  3. Immediate Decontamination Kit for Military Working Dogs in Fields

    SBC: Zymeron Corporation            Topic: CBD192001

    Military Working Dogs (MWDs) provide a valuable asset to military troops, police, and other government agencies. In recent years, the increasing deployments of MWDs in different tactical environments make them encounter much higher risk from exposure to a range of hazardous chemicals, including chemical warfare agents (CWAs), toxic industrial chemicals (TICs), and narcotics. Since there is no prot ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous System

    SBC: Fenix Research Corporation            Topic: CBD192005

    Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: Arisan Therapeutics, Inc.            Topic: CBD192006

    Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in Humans

    SBC: Equinox Ophthalmic, Inc.            Topic: CBD192005

    Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. A fast pulse, portable fast neutron source for special nuclear materials detection

    SBC: Alameda Applied Sciences Corporation            Topic: N/A

    Alameda Applied Sciences Corp proposes to develop a fast pulse, portable, fast neutron source to detect SNM in the field. Our source offers a 20ns neutron pulse with a repetition rate up to 1kHz. The goal is to develop a source with 1000hrs of continuous operation at 1E8 n/s. The Ph I program will demonstrate the critical features of the source including pulse width, reproducibility and neutron yi ...

    SBIR Phase I 2007 Department of Homeland Security
  8. High-Yield Pulsed Neutron Generator

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    A pulsed neutron generator is proposed for the detection of special nuclear material. A recently developed RF-excited plasma neutron generator will be pulsed to produce the activating neutrons whose pulse length is 100 microseconds with a fall time of less than 1 microsecond. High pulse repetition rates and high peak neutron yields can be otained depending upon the RF generator used. Using the T-T ...

    SBIR Phase I 2007 Department of Homeland Security
  9. CZT Surveillance Camera

    SBC: Aguila Technologies, Inc.            Topic: HSB071008

    The improved surveillance of radioactive sources used in hospitals, research centers, food irradiations plants and other fully legal and sanctioned industries is paramount to interrupt the terrorism value chain. This value chain relies on stealing radioactive sources from the legitimate before mentioned institutions to build radiological dispersal devices (RRD). Nowadays, radioactive sources are s ...

    SBIR Phase I 2007 Department of Homeland Security
  10. Metal-Insulator-Semiconductor Gallium Nitride Detector

    SBC: Physical Optics Corporation            Topic: HSB062007

    In response to the HSARPA need for the development of high quantum efficiency, fast photon counting detectors to read UV/visible light emitted by scintillators under gamma radiation, Physical Optics Corporation (POC) proposes to develop a new Metal-Insulator-Semiconductor Gallium Nitride (MISGaN) detector that will have high sensitivity in the UV region for use with cerium-doped crystal scintillat ...

    SBIR Phase I 2006 Department of Homeland Security
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