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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. New Topical Therapies for Psoriasis

    SBC: BETHESDA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common, inflammatory disease of the skin characterized by hyperproliferation of keratinocytes. A variety of antipsoriatic therapies are available, however, due to problems with side effects and variability in clinical response, intense clinical and commercial interest remains in the development of new treatments. In the current studies, we are in ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Isotopically Labeled Nucleotides for Biomolecular NMR

    SBC: CASSIA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to scale up the production and manufacture of high-value ribonucleoside triphosphates containing stable isotope labels. The use for these products is in biomolecular studies of RNA structure using Nuclear Magnetic Resonance (NMR) spectroscopy. The market for these products is structural biology groups in academic and industr ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Sample Processing Cartridges for Rapid PCR TB Detection

    SBC: CEPHEID            Topic: N/A

    DESCRIPTION (provided by applicant): Cepheid Inc and the New Jersey Medical School have developed an assay system that integrates sample processing and real-time PCR diagnosis into a single, hands free process. During the successful completion of a phase I STTR application we demonstrated that this system simultaneously detect the presence of Mycobacterium tuberculosis (TB) and diagnose rifampin r ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Identification of Novel ACTH Small Molecule Antagonists

    SBC: Chemdiv, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of drugs based on the MC2R antagonists will directly benefit children with CAH and Cushing's diseases, and will help us to understand MC2R's role in metabolic pathways. The long term goal of this project is to discover small molecule inhibitors of MC2 receptor and develop drug to treat several metabolic diseases including CAH and Cushing's diseases ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Diffraction From Microvolume Topaz Microprocessors

    SBC: FLUIDIGM CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): We intend to develop an improved microfluidic device that allows crystallization experiments to be interrogated directly with X-ray radiation without requiring crystals to be removed from the well. This will allow experimenters to assess the outcome of crystallization experiments on the basis of diffraction data rather than arbitrary optical judgments. Identifi ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase II: Engineering Geobacter for Enhanced Electricity Production

    SBC: GENOMATICA, INC.            Topic: BT

    This Small Business Technology Transfer (STTR) Phase II project aims to develop commercially viable bacterial strains (Geobacter sulfurreducens) for use as biocatalysts in microbial fuel cells. The research genetically manipulates these bacteria to enable the utilization of alternative substrates and increase current generation through the expression of an energy consuming futile cycle. The rate ...

    STTR Phase II 2006 National Science Foundation
  7. Ultrasound Guidance for a Laparoscopic Surgical Robot

    SBC: INTUITIVE SURGICAL            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal represents the second phase of an STTR partnership involving Intuitive Surgical Systems and Johns Hopkins University. Phase I demonstrated the feasibility and promise of integrating laparoscopic ultrasound (LUS) capability into daVinci. Phase II will develop a complete, integrated application environment and testbed surgical applications for LUS-g ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Modified HER-2 Tumor Antigens for Vaccination in Cancer

    SBC: L2 Diagnostics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer remains one of the most insidious and difficult to treat human malignancies, affecting thousands of individuals each year. Our proposed studies are aimed at developing a novel tumor immunotherapy by using cryptic peptides of Her-2 protein and modified Her-2 peptides, both of which break immune tolerance to ?self? tumor antigens expressed on breast ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Retroviral Vectors for Safe and Efficacious Gene Therapy

    SBC: Neumedicines Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I funding for this project supported the successful development of the backbone for a new generation of retroviral gene therapy vectors that contain safety and efficacy features designed to overcome the problems that have been found with retroviral vectors used in current clinical trials. The model disease targeted is the well-studied genetic disease Aden ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. STTR Phase II: Support Material Characterization for Ultrasonic Rapid Prototyping

    SBC: SOLIDICA            Topic: AM

    This Small Business Technology Transfer Research (STTR) Phase II project will complete the development of a support material for Ultrasonic Consolidation (UC) direct metal rapid prototyping and demonstrate the ability to build structures with high aspect ratios or overhanging features. This ability to apply UC to more complex shapes will enable engineers to design important parts more rapidly and ...

    STTR Phase II 2006 National Science Foundation
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