Award Data

Abstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...

Project Summary/Abstract – The EPA maintains a Toxics Release Inventory of andgt;650 toxic chemicals that are disposed or released from andgt;20,000 industrial sites in the United States, while HHS and USDA maintain a list of over 60 select agents and toxicants that pose a severe risk to human, animal, and plant health. These compounds represent only a fraction of the known and unknown environme ...

High-power, high-efficiency, broadly-tunable coherent sources in the mid-wave infrared (MWIR, λ=3–5 μm) spectral band are coveted for applications relating to infrared (IR) countermeasures, remote chemical sensing, and free-space optical communication. MWIR sources based on optical nonlinear frequency conversion can generate broadly-tunable kilowatt-level coherent radiation over the e ...

Neonatal hypoxia/ischemia is a known cause of cerebral damage resulting from inadequate blood flow and/or oxygen delivery to the infant brain before, during, or after birth. The occurrence among hospital deliveries is ~2-4 per 1000 full-term births with a drastic increase among premature newborns. The deficit in oxygen delivery to the brain results in extensive damage and severe disabilities. Rest ...

Optical photothermal IR (OPTIR) microscopy for chemical imaging of living cells at sub-micron resolution Project Summary/Abstract Photothermal Spectroscopy Corp (PSC) and Prof. Ji-Xin Cheng of Boston University in collaboration with Prof. Rohith Reddy (University of Houston) propose to develop, validate, and commercialize a novel technical called Optical Photothermal Infrared (OPTIR) spectroscopy. ...

This proposal is for a phase I/II fast track project for the STTR program with the main goal to develop a test for high sensitive detection of tau oligomers in biological fluids, which could be used for the biochemical diagnosis of Alzheimer’s disease (AD) and related tauopathies. AD is the most common dementia in the elderly population and one of the leading causes of death in the developed wor ...

Project Summary/Abstract Despite the investment of billions of dollars in biomedical research each year from NIH, barriers remain in effectively translating basic science discoveries from academia to commercial products that benefit patients. These barriers include a funding gap between basic research and commercial developments, a lack of knowledge by innovators on how to bring products to market ...

Recent breakthroughs in the material quality and fabrication methods of III-V InAs/GaSb superlattice (SL) structures with a Type II band alignment has enabled high-performance MWIR detectors and LEDs. Nanohmic Inc. in collaboration with UT Austin proposes to develop Type II InGaSb/InAs quantum dot infrared light emitting diodes (QD-IRLED) for high-power infrared scene projection. This particular a ...

The Biomagnetics Micro Dosimetry System (BMDS) program will design, model, and simulate a microdosimetry system that can measure and create a three dimensional map of weak radiofrequency signals in biological organisms. The heart of the BMDS project is the front end that delivers very sensitive, broad band measurements with high spatial resolution. The front end is a valuable tool in the investiga ...

Currently fielded multi-beam CDL systems have been developed in an ad-hoc manner consisting of a collection of poorly integrated off the shelf technologies where controllers, radios, routers, firewalls, encryptors, and antennas are bolted together to reduce time to field. Proprietary API’s, electrical interfaces, and hardware interfaces impede the success of the approach and result in a sub ...