Award Data

During altitude-induced hypoxia, operator cognitive and physical capacity degrades, compromising individual and team performance. Cognitive degradation is linked to falling brain energy levels, increased reliance on anaerobic energy production and lactate accumulation. Ketones are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies demonstrated that ...

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

Special OperationsForces (SOF)are an integral aspect of the US military. SOF operators are among the most elite and highly qualified individuals in the U.S.military. As such, extraordinary physical and mental demands are placed upon them to excel in extreme environments for extended periods of time. This unrelenting cycle of combat deployments and intense pre-deployment training shortens the funct ...

Stottler Henke proposes PaCT, leveraging our related past work in computer vision and machine learning. Drawing from techniques used in ExPATSS, a Phase II SBIR effort slated for transition to the Naval fleet, PaCT will perform bacterial characterization using features derived from the phenotype of the bacteria. PaCT will predict bacterial characteristics such as pathogenicity, antibiotic resistan ...

As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, the they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many ...

The use of continuous glucose monitors can be an invaluable management tool for patients afflicted by glycemic variability due to critical illness or trauma. Maintaining stable glucose levels enhances health and lowers care costs, and individuals equipped with continuous glucose data have significantly improved outcomes. Profusa has developed highly miniaturized, injectable, tissue-like, glucose s ...

Perceptronics Solutions and the USC Computer Science Department are please to submit this proposal for a Phase II continuation of its STTR Phase I project to develop an Adaptive Rapid Team Formation System (ARTFS). The present proposal is a joint effort of Perceptronics Solutions, Inc. and Aptima, Inc., who have combined forces to develop together a new Collaborative Assistance and Rapid Team Op ...

The increasing use of video in force protection, autonomous vehicles reconnaissance, and surveillance in general has created a great demand for automated analysis and monitoring. It is infeasible to have humans monitoring and analyzing the vast amount of video used in such surveillance, and automated analysis yields hope to ease the burden and increase the amount of information extracted from col ...

A new method of manufacturing of deep brain stimulation devices is proposed. We will use proprietary method of processing of carbon nanotubes into ultrastrong and highly conductive thin sheets. Flexibility of the sheets and special electrode design will make possible effective integration of the designed implants into the brain tissues. This will greatly reduce inflammation which will be tested ...

The development of early detection methods to aid in the identification of virulent infectious pathogens is of strategic importance so that exposed warfighters and other individuals can be treated early or appropriately quarantined. We are currently developing a nucleic acid-based assay that can selectively and sensitively detect and quantify the RNA or DNA specific to a broad range of pathogens i ...