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Award Data
The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
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Human Performance Optimization: Ketone Esters for Optimization of Operator Performance in Hypoxia
SBC: HVMN Inc. Topic: SOCOM17C001In the setting of altitude-induced hypoxia, operator cognitive capacity degrades and can compromise both individual and team performance. This degradation is linked to falling brain energy (ATP) levels and an increased reliance on anaerobic energy production from glucose. Ketone bodies are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies have sho ...
STTR Phase I 2018 Department of DefenseSpecial Operations Command -
A Method to Increase Buprenorphine Treatment Capacity and Effectiveness
SBC: CBT4CBT, LLC Topic: R42The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioiddependent patientsOvermillion people in the US are addicted to opiatesProviding effective agonist therapymethadone or buprenorphinecoupled with behavioral counseling greatly improves outcomesreduces morbidityand reduces societal costsMethadone maintenance treatment has been limited due to complex sta ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Interventions to Improve Reproductive Health among Adolescents
SBC: DFUSION INC. Topic: NICHDAlthoughyear olds are onlyof the U Ssexually active populationthey account for nearlyof themillion new cases of sexually transmitted infectionsSTIeach yearAlthough historically lowthe U Steen pregnancy rate continues to be one of the highest in the developed worldEvidence based prevention efforts can help avoid the costs and health consequences associated with STIs and unwanted teen pregnancy amon ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Novel Indication for Myeloid Progenitor Use: Induction of Tolerance in Solid Organ Transplantation
SBC: Cellerant Therapeutics, Inc. Topic: NIAIDPROJECT SUMMARY State of the art techniques result inyear solid organ graft loss ofto overin cardiopulmonary organ transplantationEstablishment of donor specific immunological toleranceDSITa condition in which a recipient accepts a transplant without immunosuppressionwhile retaining the ability to fight infectionswould reduce graft loss and transplant related complicationsThe only identified metho ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Therapeutic that Harnesses Microtubules to Promote Cavernous Nerve Regeneration after Radical Prostatectomy
SBC: MicroCures Inc. Topic: 300Radical prostatectomyRPis a commonly used treatment option for localized prostate cancerUnfortunatelythe procedure carries a risk of post surgical complications including a high risk of erectile dysfunctionEDAccording to The Prostate Cancer Outcomes Studyvirtually all men experience ED after surgeryincluding a profound loss of nocturnal erectionsThe Prostate Cancer Outcomes Study further reveals t ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Therapeutic that Harnesses MIcrotubules to Enhance Corneal Wound Healing Following an Alkaline Burn
SBC: MicroCures Inc. Topic: NEIThe cornea is one of the most important tissues in the eye and its transparency is critical for good visual function in humansCorneal tissue injuries are the most common everyday issue for practicing ophthalmologists and can run the gamut in severityIn severe modelssuch as corneal alkaline burnsextensive healing is needed and often the burn victim is left with reduced visual acuityHealing of large ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Veristride STEP-R: an interactive verbal/auditory gait trainer
SBC: Veristride, Inc. Topic: 600Veristride IncProject Summary When surveyedof stroke survivors said the ability toget out and aboutis considered between important and essential for a better lifeHoweverthat desire falls short of reality for most stroke survivorsOftenwalking across a neighborhood street or from a car to a home is an insurmountable task with little opportunity for working on improvement in gaitOnce insurance covera ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Automated preparation of single-cells and nuclei from solid tissues
SBC: S2 GENOMICS, INC Topic: 172Project Summary AbstractThis project designsdevelopsand automates a novel system to process solid tissue into single cellssingle nucleiand high molecular weight DNA using disposable cartridges without user interventionThe system will support downstream single cell RNA or DNA sequencingsingle nuclei RNA or DNA sequencingand long read sequencers and optical mappingThe long term goal of the project i ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Advancing Formulation of STING agonist for Universal Flu Vaccine
SBC: IMMvention Therapeutix, Inc. Topic: NIAIDSummary Influenza virusa member of the orthomyxovirus familyhas three different types that infect humansABand CTypes A and B produce annual epidemicsand type A influenzawhich resides asymptomatically in birdscan cause pandemic infections in humansIn addition to common flu like symptomse gfeverchillsmalaisemuscle painin susceptible populations influenza can induce potentially fatal secondary compli ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic inhibition of Fas-mediated retinal cell death and inflammation in dry AMD
SBC: ONL Therapeutics, Inc. Topic: NEIPROJECT SUMMARYABSTRACT Age related macular degenerationAMDis the leadingand due to the aging baby boomersa growing cause of irreversible vision loss in the United Statesand is strongly associated with exposure to cigarette smokeCSand high fat dietsHFDWhile effective treatment is available for neovascular AMDthe AREDS II antioxidant vitamins are the only proven treatment for intermediate dry AMDUn ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health