Award Data

The goal of this Phase I SBIR is to define a set of algorithms that will detect and characterize static man-made objects highly obscured by foliage within multi-view, multi-channel optical data collected passively from UAVs or other aerial platforms. The proposed algorithm stream will be constructed so as to comprehend and mitigate real-world interfering effects such as clouds, smoke and haze. Dur ...

Bioren's technology provides an efficient, automated, in vitro system to generate and optimize antibodies and antibody fragments through a rational, hypothesis-driven approach. Bioren's patented technology is based on synthetic oligonucleotide chemistry to create defined antibody mutations. Hypotheses regarding the impact of a specific amino acid's side-chain chemistry within the antigen binding ...

Since 1993, ASZM-TEDA carbon has been the standard filtration material used by the U.S. military for protection against nerve, blister and blood agents, and other maliciously delivered air contaminants. Although ASZM-TEDA effectively removes these contaminants, alternative air filtration media are sought to ameliorate bulky, unwieldy designs necessitated by current technology. Additional improveme ...

Two distinct designs with performance characteristics for analyzers consistent with the solicitation requirements were delivered in Phase 1. The Phase 1 research and modeling results have been sufficiently conclusive to indicate feasibility of both designs. The more novel of the two designs is proposed: a hybrid magnetic/electrostatic analyzer that features very high collection and transmission ef ...

Two distinct designs with performance characteristics for analyzers consistent with the solicitation requirements were delivered in Phase 1. The Phase 1 research and modeling results have been sufficiently conclusive to indicate feasibility of both designs. The more novel of the two designs is proposed: a hybrid magnetic/electrostatic analyzer that features very high collection and transmission ef ...

Fabrication of stable, nearly 100% internal carrier collection efficiency silicon photodiodes (AXUV diodes) for 1 nm to 600 nm photons was successfully demonstrated by us several years ago. Owing to their excellent characteristics, these devices are being used by NIST as transfer standards in 5 nm to 250 nm range and aboard SOHO, SNOE and TIMED instruments for the EUV solar spectrum studies. Alt ...

Light-weight, high-performance subcomponents, particularly filters and pumps, are needed to make a portable water purifier that can produce clean water from any source. At present, some of the principal problems that hamper this effort include the heavy weight of the pumps and their motors and the large size and fouling rate of pre-treatment filters. These problems may be overcome using Los Gato ...

An innovative optical system with 500X higher ¿tendu and spatial resolution will be designed for CCD-based bistatic lidar. A 100¿ vertical field of view is required to image the laser beam from the ground through the boundary layer, but only a few degrees are required in the horizontal direction. The proposed design is based on dividing the vertical field of view into N sectors, using 1D rasteri ...

The threat of bioterrorism has increased the demand for advanced technologies to rapidly and accurately detect and identify numerous pathogens at the species and strain level in air, water, food and other matrices. Advanced automated instrumentation with low operating costs that can be rapidly adaptable to new pathogens or agents is required. This proposal describes rapid application of microflu ...

PCR and antibody-based devices are currently the primary platforms for bioagent detection. PCR offers high sensitivity and specificity, but has limited effectiveness for toxins (detects residual DNA, if any, in toxin preparations) and requires thermal cycling equipment, extensive sample preparation, and complex reagents. Antibodies, which utilize relatively simple chemistry, are effective for bo ...