You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation of Glioblastoma
SBC: NUVOX PHARMA, L.L.C. Topic: 102Glioblastoma multiforme (GBM) is a malignant primary brain tumor affecting about 12,000 new cases per year in the U.S. Average survival is only about 14-15 months. Radiation (RT) is most commonly administered as 30 fractions of 2 Gray each over 6-weeks with concomitant temozolomide (TMZ). GBM tumors are hypoxic. The primary mechanism of RT is creation of singlet oxygen; hypoxia within GBM adversel ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
An Integrated Microarray Printing and Detection System
SBC: BIOSENSING INSTRUMENT INC Topic: 400DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Microneedle Delivery of Zanamivir for Treatment of Influenza Infections
SBC: TSRL, INC. Topic: NIAIDAbstract Yearly influenza epidemics strike millions of peoplecausing up todeathsFatality caused by most seasonal influenza viruses is ltbut with significant mortality in the young and the elderly populationsWhen a new pathogenic influenza strain enters the populationa pandemic could kill tens of millions of people with a negative economic impact estimated to be overbillion dollarsInfluenza virus i ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
High throughput multiplexed characterization and modeling of antibody antigen binding with application to HSV
SBC: Carterra, Inc. Topic: NIAIDAbstract All therapeutic antibodies and most vaccines critically depend on the ability of antibodies to specifically recognize particular antigens consequently detailed characterization of antibody antigen binding can provide invaluable information to understand and guide development Unfortunately due to the time and expense required atomic resolution structure determination is typically use ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of a DNA Aptamer Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials
SBC: ApolloDx , LLC Topic: NIDADevelopment of a DNA Aptamer Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials Thirty to over eighty percent of patients enrolled in pharmaceutical clinical trials do not comply with trial protocols by discarding the drug under investigation or not using the proper dosages This common practice compromises the medica ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment
SBC: NeuroEM Therapeutics, Inc. Topic: 104ABSTRACT Formation of misfolded protein oligomers in neurons is an early and causative event in a variety of neurodegenerative diseases such as Alzheimer s Disease amyloid and tau oligomers Fronto temporal lobe dementia tau oligomers and Parkinson s Disease synuclein oligomers These toxic oligomers share a common aggregation mechanism that involves formation of hydrogen bonds betwee ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
OpenBeds: Improving the Delivery of Care for Patients with Drug Addiction
SBC: Openbeds Inc. Topic: NIDAThere is an urgent need for more effective mechanisms that leverage current technologies and best practices to both identify capacity and refer patients to drug treatment facilitiesThe applicant organizationOpenBeds Incis partnering with the non profit MESH Coalitionthree of the largest health care systems offering drug treatment in Indiana and the Indiana Division of Mental Health and AddictionDM ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Next Generation Western for high-throughput and high-content protein analysis
SBC: LI-COR, Inc. Topic: 400Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Geostatistical software for space-time interpolation and uncertainty modeling
SBC: BIO-ANALYTICS, INC. Topic: NIEHSDESCRIPTIONprovided by applicantA key component in any investigation of association and or cause effect relationships between the environmente gair pollutionheat wavesand health outcomese gasthmaheart diseasecanceris the availability of accurate models of exposure at the same geographical scale and temporal resolution as the health outcomesThe computation of human exposure is particularly challeng ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health