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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. HT-production of Abs using Interaction Trap in Yeast

    SBC: AFFOMIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Affomix would like to commercialize antibody chips to enable researchers to study the human proteome. Currently, researchers use gene chips as a surrogate means to estimate the concentration of the vast variety of pro teins in cells and tissues. But given the choice, most researchers would prefer to study the proteins directly because of the; i) poor correla ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Huperzine for Cognitive and Functional Impairment in Schizophrenia

    SBC: BIOMEDISYN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Schizophrenia affects approximately 3 million people in the US, and it is one of the leading causes of disability. Currently available drugs are only partially effective, particularly for the cognitive impairments that contribute to functional loss. A new investigational drug, BMD-101, has been shown to have neuroprotective, neurotrophic, cholinergic, and dopa ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Chronic Disease Management System

    SBC: CIELO MEDSOLUTIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I STTR is focused on testing the feasibility of developing a scalable, commercial health information system based on ClinfoTracker, an existing system developed in an academic setting. The proposed system can significantly impact the recognition, tracking and management of chronic diseases such as cancers. By tracking and managing activities and out ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Minimally-Invasive Image-Guided Therapy for Cancer Treatment

    SBC: CONTRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a technology and eventually a minimally-invasive commercial system for image-guided photodynamic therapy for cancer. This is certainly in keeping with NCI's focus o n imaging in vivo for cancer screening, diagnosis, progression, image-guide therapy, treatment monitoring, and recurrence. In studies conducted ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Genetic Programming to Predict Clinical Outcome from Transcript Quantification

    SBC: GENETICS SQUARED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this Phase I study is to establish the technological merit and feasibility of our proposed approach to developing and then commercializing a pair of companion prognostics for newly diagnosed non - muscle invasive Ta T1 urothelial carcinoma (UC) of the bladder that accurately predicts the relative chances of tumor recurrence and progress ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Software for stochastic musculoskeletal modeling

    SBC: GRIZZLY MOOSE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Introduction: Computational models of human joint mechanics have become common in musculoskeletal science. Although existing deterministic models have provided significant insight into musculoskeletal mechanics, they c annot explain some important phenomena. The discrepancy between model predictions and experimental observations can be resolved by treating mod ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. The Development of Cross-Platform Quantitative Standards for Diagnostic Immunohis

    SBC: HISTORX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Patient-specific therapies targeted to the phenotype of individual tumors represent the future of cancer treatment. The prototypes for this type of therapy are Herceptin and Tamoxifen, which are only given to patients e xpressing a particular level of HER2 and estrogen receptor (ER), respectively. It is likely that dozens of such therapies will be developed for ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Tick Midgut Thrombin Inhibitor as a Vaccine Target

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): We seek in this proposal to develop a tick vaccine to block tick feeding and pathogen transmission to the vertebrate host. Ticks can harbor bacterial, viral and protozoan pathogens and infected ticks transmit pathogens to the mammalian host during feeding, causing human and cattle disease worldwide. Ixodid ticks are obligate hematophagous arthropods that feed ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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