Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be to develop engineered bacteria with the ability to oxidize the copper mineral chalcopyrite and gold. The majority of copper reserves are in chalcopyrite, which currently requires smelting. The US copper mining industry, due to regulatory restrictions, has a limited smelting capacity forcing US ...

This project will develop a flexible longitudinal electron optical system based on high-precision radio-frequency cavities for short and intense electron bunch compressions, both in the energy and time domains. The proposed system is designed to be insertable into an existing transmission electron microscope column to upgrade its temporal resolution. Active phase-space control enables broad ranges ...

According to a report by the Hydrogen Council, a global lobby set up in January 2017 by Toyota and Air Liquide that includes 27 members such as automakers Audi, BMW, Daimler, Honda and Hyundai, and energy firms Shell and Total, increasing the use of hydrogen in power, transport, heat and industry could deliver around one fifth of the total carbon emissions cuts needed to limit global warming to sa ...

Naval aircraft components are routinely made of 7000 series aluminum alloys due to their strength, weight and fatigue properties. Present Additive Manufacturing (AM) processes falls short of producing 7000 series Al alloys successfully due to lack of porosity, thermal and composition control. In-situ methods implemented to date largely only yield information about the component surface and other m ...

The broader impact/commercial potential of this STTR project stems from the costs to U.S. food producers of outbreaks of animal diseases. Producers of poultry, pork, and other food proteins lose more than $1B each year to infectious diseases, including some that are transmitted through the air. For diseases having an airborne transmission route, protective technologies that are available are few a ...

The discovery of large shale gas reserves in recent years has resulted in the reduction of natural gas price and a need to develop new applications for the available resource. Upgrading shale gas to liquid fuels which are more easily transportable and have greater economic value can result in significant benefits to the US. Coupled with this challenging problem the DOE has a goal of further develo ...

The proposed Bifunctional Regenerative Electrochemical Air Transformation for Human Environments (BREATHE) for life support and habitation is part of the atmosphere revitalization equipment necessary to provide and maintain a livable environment within the pressurized cabin of crewed spacecraft. Sustainable Innovations (SI) has developed a novel solid state technology for gas compression based on ...

Project Summary Abstract PreDxion BioLLC is a precision medicine diagnostic company developing an assay platformthe MicroKineassay cartridge and readerthat measures serum proteins in less thanminutes from a single drop of bloodThis fastactionable information allows for the first time individualized precision medicine aimed at reducing pediatric morbidity and mortality in pediatric sepsisthe number ...

Project Summary A research plan is proposed to engineer goats that produce fully human immunoglobulinThese animals will be evaluated as a candidate platform system for production of both targeted therapeutic immunoglobulin as well as reagent antibodies for standards and controls of serological assays of human clinical samplesPrevious studies have demonstrated that ungulates such as cattle can prod ...

Abstract Currentlyclinically used drug abuse medications exist for treatment of addiction to opiatesalcoholand nicotinebut not cocaineThe objective of the proposed project is to test the hypothesis that the partial kappa agonist PPLcan be effective as a pharmacotherapy for treatment of cocaine abuseBecause of chronic drug induced changes in the kappa opioid receptor systemkappa receptor directed c ...