Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

Displaying 1 - 10 of 32965 results
  1. Feasibility study of a novel noninvasive RF sensor for blood pressure measurements.

    SBC: Blumio, Inc.            Topic: NCCDPHP

    PROJECT SUMMARYABSTRACTHigh blood pressureor hypertensionis an important public health challenge because of its high prevalence and its role in increasing risk for a variety of other diseasesAccording to the American Heart Associationapproximatelyout of everyadults in the United States has hypertensionand the situation is projected to worsen with the percentage rising to approximatelyof the adult ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Implantable Peripheral Nerve Stimulator for Treatment of Phantom Limb Pain

    SBC: RIPPLE, LLC            Topic: 999

    Abstract Chronic phantom limb painPLPhas been reported to inflict as many asof people with amputationsPLP is described as feeling like burningtwistingitchingor pressure in part of the missing limbThese painful sensations have a substantial negative impact on quality of lifepeople who suffer PLP have high rates of depressiondifficulty sleepingregular absences from workdissociation with family frien ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Targeting lipid rafts for treatment of migraine

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NINDS

    PROJECT SUMMARY Migraine is a highly prevalent condition with an extraordinarily negative impact on quality of life and represents a heavy socioeconomic burden to the societyprimarily because of decreased working efficiency and workdays lostManagement of migraine has become increasingly pharmacological during recent yearsWhile several therapeutic options existmost of the prophylactic drugs current ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Novel monoclonal antibody for single dose treatment of acute CNS injury

    SBC: OncoSynergy, Inc.            Topic: NINDS

    PROJECT SUMMARY Traumatic brain injuryTBIrepresents a significant societal and economic impactTo datethere are no FDAapproved pharmacotherapies to prevent or reverse TBIThe standard of care in an emergency setting focuses first on stabilizing the patient and secondly on management of cerebral hemodynamicsThe patient may undergo surgery to remove hematomasrepair skull fracturesand relieve intracran ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Pre-clinical evaluation of DT-001, a small molecule antagonist of MD2-TLR4 for utility in the treatment of pain.

    SBC: Douleur Therapeutics Inc            Topic: NINDS

    Project Summary AbstractUpwards ofmillion individuals are afflicted by chronic pain in the US alonewithmillion of these individuals suffering from neuropathic painOn a global scalechronic pain affectsbillion individualswithwho endure lower back painFrom a clinical perspectivethe International Association for the Study of Pain approximates thatinpatients present with painand on an annual basisinpat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Intelligent Fuel Transport Monitor

    SBC: Hedgefog Research Inc.            Topic: AF191047

    The problem of measuring the flow of fuel in the testing of military aircraft has, so far, been addressed with the use of conventional inline flowmeters, which require lengthy installation/removal times and substantial modification of the fuel lines to allow sensor insertion.Commercial non-invasive flowmeters do not possess the accuracy and robustness required by the U.S. Air Force in its flight t ...

    SBIR Phase I 2019 Department of DefenseAir Force
  7. Development of A Narrow Spectrum Anti-Tubercular Agent

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    Abstract Complex and lengthy treatment regimens coupled with rising drug resistance underscore the urgent need for new and better drugs to treat tuberculosisTBcaused by the bacterium Mycobacterium tuberculosisMtbCurrent treatment regimens for drug resistant TB involve the use of costlyless effectiveand toxic drugs that must be continued for up tomonthsThe work proposed here focuses on a proprietar ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Targets of Acquired Tick-Resistance As Anti-Tick Vaccines

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACTThis proposal seeks to develop a novel vaccine against pathogens transmitted by the blacklegged tickIxodes scapularisby targeting tick salivary proteinsSalpscritical for tick feedingIscapularis Salps provide functions critical for evading host defense responses detrimental to the tickFurtherthese salivary functions are also co opted by tick transmitted pathogens to ensure their survival in ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of world's first fully human broad spectrum anti-snake venom

    SBC: Distributed Bio, Inc.            Topic: NIAID

    ABSTRACT In this Phase I SBIR grantDistributed Bio proposes to develop the next generation of safer and more effective antivenom biotherapeutics by isolating and characterizing broadly neutralizing fully human antivenom antibodies for treating snakebite envenomingInsnakebite envenoming continues to be ranked on the World Health Organization s list of neglected tropical diseaseskilling betweenpeopl ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. BCN057 as a mitigator of Radiation Induced Gastrointestinal Syndrome

    SBC: BCN Biosciences L.L.C.            Topic: NIAID

    Project Abstract Currentlythere is a need for drugs that mitigate acute radiation induced gastrointestinal syndromeRIGSRisk of large populations encountering radiation exposure is real and growing due to the proliferation of rogue nonstate actorspolitical instability resulting in potential access of nuclear weapons by terroristand by natural disaster as evidenced by the release of radioactive mate ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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