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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Targeting lipid rafts for treatment of migraine

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NINDS

    PROJECT SUMMARY Migraine is a highly prevalent condition with an extraordinarily negative impact on quality of life and represents a heavy socioeconomic burden to the societyprimarily because of decreased working efficiency and workdays lostManagement of migraine has become increasingly pharmacological during recent yearsWhile several therapeutic options existmost of the prophylactic drugs current ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Novel monoclonal antibody for single dose treatment of acute CNS injury

    SBC: OncoSynergy, Inc.            Topic: NINDS

    PROJECT SUMMARY Traumatic brain injuryTBIrepresents a significant societal and economic impactTo datethere are no FDAapproved pharmacotherapies to prevent or reverse TBIThe standard of care in an emergency setting focuses first on stabilizing the patient and secondly on management of cerebral hemodynamicsThe patient may undergo surgery to remove hematomasrepair skull fracturesand relieve intracran ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Pre-clinical evaluation of DT-001, a small molecule antagonist of MD2-TLR4 for utility in the treatment of pain.

    SBC: Douleur Therapeutics Inc            Topic: NINDS

    Project Summary AbstractUpwards ofmillion individuals are afflicted by chronic pain in the US alonewithmillion of these individuals suffering from neuropathic painOn a global scalechronic pain affectsbillion individualswithwho endure lower back painFrom a clinical perspectivethe International Association for the Study of Pain approximates thatinpatients present with painand on an annual basisinpat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Targets of Acquired Tick-Resistance As Anti-Tick Vaccines

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACTThis proposal seeks to develop a novel vaccine against pathogens transmitted by the blacklegged tickIxodes scapularisby targeting tick salivary proteinsSalpscritical for tick feedingIscapularis Salps provide functions critical for evading host defense responses detrimental to the tickFurtherthese salivary functions are also co opted by tick transmitted pathogens to ensure their survival in ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. NOVO-118 as a therapeutic to promote remyelination in in vivo models of MS

    SBC: Novoron Bioscience Inc.            Topic: NINDS

    Project Summary Multiple sclerosisMSis a neurodegenerative disease in which myelin of the central nervous systemCNSis destroyed by a self reactive immune responseThis demyelination is accompanied by the death of the myelinating cells themselvesthe oligodendrocytesRepeated bouts of demyelination leave the denuded CNS neurons vulnerable to degradation and is the major cause of neuronal dysfunction a ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Targeting lipid rafts for treatment of asthma

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NIAID

    PROJECT SUMMARY Asthmacharacterized by airways obstruction with symptoms of wheezingshortness of breathchest tightness and consequently coughremains a significant health problemWhile advances in bronchodilatorcorticosteroid and Thtargeting therapy allow for well controlled asthma in a large population of patientssubjects with severecorticosteroid resistant asthma require frequent hospitalizations ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. STTR Phase I: Computerized System for Detection, Assessment, and Visualization of Intraoperative Bleeding During Robotic and Laparoscopic Surgery

    SBC: REDIMINDS, INC.            Topic: R

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to reduce the morbidity and mortality of patients undergoing surgery. Inadvertent bleeding during surgery represents a critical problem that occurs during all types of procedures on millions of patients around the world. This project will advance a robotic surgical tool system using artific ...

    STTR Phase I 2020 National Science Foundation
  8. STTR Phase I: A Roadside Marijuana Breathalyzer to Rapidly Screen for Cannabinoid Sobriety

    SBC: SEACOAST SCIENCE, INC.            Topic: BT

    The broader impact of this Small Business Technology Transfer (STTR) Phase I project will be an affordable, portable breath analysis device to detect marijuana intoxication. First responders, law enforcement, medical professionals, cannabis users, and the general public will benefit from an analytical tool that allows fast and accurate screenings of cannabis impairment. An estimated 37,000 people ...

    STTR Phase I 2020 National Science Foundation
  9. STTR Phase I: SondeFlux, a novel, low-cost, noninvasive device to detect and characterize the presence or absence of a bolus in the upper esophagus.

    SBC: REFLODX, LLC            Topic: BM

    The broader impacts/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to investigate novel noninvasive methods for detecting and quantifying material in the upper esophagus. Reflux occurs when a bolus of gastric contents flows in reverse from the stomach into the esophagus. Symptoms of reflux can include chronic cough, choking, difficulty breathing or swallo ...

    STTR Phase I 2020 National Science Foundation
  10. STTR Phase I: Vertical Structure Thin Film Transistors for High Performance Displays and Internet of Things Devices

    SBC: Solsona Enterprise LLC            Topic: S

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to improve the performance of flat panel displays of various form factors and sizes. One of the key subsystems of a flat panel display is a TFT (Thin Film Transistor) backplane that drives the pixels in the panel. There are increasing demands for improved resolution and frame rate in displa ...

    STTR Phase I 2020 National Science Foundation
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