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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Adaptive camera to display mappings using computer vision

    SBC: POLAR RAIN, INC.            Topic: N/A

    The video surveillance industry is experiencing dramatic change with the move from analog to digital video. Command centers need to have coordinated viewing of multiple camera feeds at one time, and the ability to switch automatically between feeds and display relevant patterns. Conventional security control rooms include a bank of monitors connected through a switch to an array of security camera ...

    STTR Phase I 2006 Department of Homeland Security
  2. A 3-D Interactive Atlas of the Human Skull

    SBC: BROWN AND HERBRANSON IMAGING            Topic: N/A

    DESCRIPTION (provided by applicant): Broad long term objectives and specific aims: The long-term objective of this project is to develop a digital anatomical research resource library of very high-resolution computational models, and imaging data sets. Our objective is to produce an anatomical library otf the complete human skeleton. The implications of this project, both scientific and social are ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. A Genetic Test for Drug-Induced Dyskinesia Risk

    SBC: KOVOGEN            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is to develop a genetic test, involving the protein, RGS9, to identify patients that are at risk for developing tardive dyskinesia (TD) or L-DOPA induced dyskinesia (LID). Antipsychotic drugs have revolutionized the treatment of schizophrenia and psychotic disorders but a debilitating side-effect of "typical" antipsychotics is TD, ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. A HUMAN MONOCLONAL COCKTAIL FOR RSV IMMUNOTHERAPY

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The central goal of this application is to develop a combination product comprising two fully human monoclonal antibodies (mAbs) produced in plants for the prevention of serious disease caused by respiratory syncytial virus (RSV). RSV causes high morbidity and mortality in certain neonate populations as well as in the elderly and in bone marrow transplant patie ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. An Epithermal Neutron Source for Cancer Therapy

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a commercial neutron source for the treatment of brain and liver cancer based on boron neutron capture therapy (BNCT). Boron-containing compounds are injected into a patient's bloodstream and accumulate in a malignant tumor. When irradiated with neutrons, the boron atoms preferentially capture neutrons and decay, releasing short-range radi ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Antivirals Targeting Flavivirus Envelope Proteins

    SBC: L2 Diagnostics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. A Wearable Multi-Sensor Navigation Device for the Visually Impaired

    SBC: CASTLEROCK ENGINEERING            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this application is to develop a wearable multi-sensor way finding device for the visually impaired that can function reliably both indoors and outdoors. The Phase I specific aims are to: 1) assemble and test a hardware platform that consists of a pocket-size computer and four sensors: a wireless signal receiver inside a wearable comp ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Botnet Analytics Appliance (BNA)

    SBC: MILCORD LLC            Topic: N/A

    As reported by Internet security threat reports, Bot networks are becoming the focal point for cybercriminals. Milcord and the University of Wisconsin, responds to this challenge with our proposal ¿ a ¿Bayesian Activity Monitor for Botnet Defense¿ (BAM-BD). In this proposal, we will research, design, and develop a botnet detection and mitigation tool that automatically classifies botnet behavio ...

    STTR Phase I 2006 Department of Homeland Security
  9. Broad-Spectrum Therapeutic Human Antibodies for Dengue Virus Infections

    SBC: L2 Diagnostics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop antibody therapeutics to treat life-threatening flavivirus infections. Our working hypothesis is that antibodies recognizing specific, highly conserved envelope protein epitopes can prevent and treat infection by several different flaviviruses, including all four serotypes of dengue virus and West Nile virus (WNV). ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Carboxylated polysaccharides for drug delivery to the eye

    SBC: BIOPOLYMER INNOVATIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many Americans suffer from ocular diseases which require application of topical therapeutic agents. These diseases range from bacterial conjunctivitis to intraocular inflammation. Keratoconjunctivitis sicca (dry eye) affects nearly 30 million people. Glaucoma affects 2 to 3 million Americans. Topical treatments exist but their ability to deliver drugs to the ey ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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