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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 12233 results
  1. Adaptive Mechanical Models for Realistic Radiation Sterilization Simulations

    SBC: TRIPLE RING TECHNOLOGIES INC            Topic: FDA

    Project Summary Medical Device development has an underlying paradigm to reduce risk early in the development cycle. Developers are using computational tools such as finite element analysis to mitigate risks from thermal loads, mechanical stresses etc. There is one exception to this paradigm: sterilization validation. Sterilization validation is addressed late in the development cycle as an actual ...

    SBIR Phase I 2023 Department of Health and Human ServicesFood and Drug Administration
  2. Extended half-life GlyTR1 combined with checkpoint blockade for Cancer Immunotherapy

    SBC: GLYTR THERAPEUTICS, INC.            Topic: 102

    AbstractTreatment of non-resectable recurrent/metastatic solid cancers is currently palliative only and there is an urgent unmet need for novel mechanisms of action and additional paradigm shifting therapeutic options. Antigen- targeting cancer immunotherapies such as bi-specific antibodies (eg Bi-specific T cell engager or BiTE’s) provide a unique approach for cancer immunotherapy. However, app ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Visual Augmentation Systems (VAS) Range Finder

    SBC: Maztech Industries LLC            Topic: SOCOM234003

    IERUS is developing a novel phased array ground terminal aperture architecture for the DoD's next generation of satellite constellations. With the proliferation of high-bandwidth satellites across LEO, MEO, and GEO, there is a need for SWaP-C optimized user terminal apertures. The IERUS solution implements scalable and mission-set reconfigurable technologies to enable rapid transition into operati ...

    SBIR Phase I 2023 Department of DefenseSpecial Operations Command
  4. Visual Augmentation Systems (VAS) Range Finder

    SBC: ATTOLLO ENGINEERING, LLC            Topic: SOCOM234003

    Augmentation Systems (VAS) Range Finder. It provides opportunities for day/night observation and range measurement in a small, easy-to-use device. We tradeoff features and SWAP-C to determine optimal combinations and document them in a feasibility study. Novel methods of presenting ranges are further. investigated and discussed.

    SBIR Phase I 2023 Department of DefenseSpecial Operations Command
  5. Point of Care HPV 16/18/45 DNA Test for Cervical Cancer

    SBC: CROSSLIFE TECHNOLOGIES INC.            Topic: 102

    Point of Care HPV 16/18/45 DNA Test for Cervical Cancer. CrossLife Technologies Inc. Project Summary/Abstract Human cervical cancer is the fourth most common cancer among women worldwide [1]. Despite cervical cancer has been thoroughly studied and the mortality has been significantly reduced through efficient screening, these preventive programs are found to be less effective in developing countri ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Quantifying microstructural changes in Alzheimer's disease using Restriction Spectrum Imaging

    SBC: Cortechs Labs, Inc.            Topic: NIA

    Project Summary/Abstract The overall goal of this project is to deliver an automated diffusion image analysis tool to be used in a clinical setting that quickly evaluates the diffusion images in conjunction with MR volumetric images and reports diffusion-based microstructural parameters derived from segmented anatomical locations to determine Alzheimer’s disease status of patients. Alzheimer’s ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Quantitative Modeling Software with Applications to Medical Decision Making

    SBC: Berkeley Madonna, Inc.            Topic: NLM

    Project Summary/Abstract In recent years, health care systems and physicians have made concerted efforts to practice evidence-based medicine and provide patients with the best available information when making choices about their medical care. However, medical decisions are often complex with many uncertainties and potential outcomes to consider, some beneficial and some adverse. A popular analyti ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Next generation MEMS-VCSEL technology for ultra-low-cost dental and periodontal swept source optical coherence tomography imaging

    SBC: PRAEVIUM RESEARCH INC            Topic: NIDCR

    This proposal aims to enable a new generation of high-speed, low-cost, wavelength-flexible swept source optical coherence tomography (SS-OCT) imaging device technology targeting applications in dental imaging and based on microelectromechanical systems vertical cavity surface emitting lasers (MEMS-VCSELs) and planar lightwave circuits (PLCs). MEMS-VCSELs provide an unmatched combination of high an ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Leveraging remote blood pressure monitoring and interpretable machine learning to improve clinical workflows for hypertensive disorders of pregnancy

    SBC: DELFINA CARE INC.            Topic: NICHD

    Project Summary/Abstract: Hypertensive disorders of pregnancy (HDP) are a leading cause of pregnancy-related deaths in the United States. Specific interventions, such as nutrition counseling and prophylactic aspirin use, are known to prevent the onset and exacerbation of HDP. However, current approaches to identify patients early in pregnancy are limited due to challenges collating patient data fr ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Mercato Thriving Communities Healthy Food Access Initiative

    SBC: MERCATO, INC.            Topic: CDC

    Abstract. Residents with a chronic lack of access to healthy food resources are at greater risk of being obese and developing obesity related chronic diseases. These diseases include diabetes, several types of cancers, cardiovascular disease, hypertension, and osteoarthritis which can decrease longevity and quality of life and represent rt10% of total health care expenditures annually. Unfortunate ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
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