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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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O-Glycan-dependent Immunotherapy for Cancer
SBC: GLYTR THERAPEUTICS, INC. Topic: 102Abstract For decadesthe treatment of cancer has relied on surgical resectionchemotherapy and or radiotherapyRecentlya number of immune based therapies have provided promising new approaches for cancer treatmentThe two most potent immunotherapies are monoclonal antibodymABbased bi specific proteinseg Bispecific T cell engagersBiTEand engineered Chimeric Antigen Receptor T cellsCAR TBoth act by indu ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Administrative Supplement to restore fee funds
SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC. Topic: NINDSProject Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Inter-examiner Agreement of a Novel Device for the Measurement of Cervical Dilation in Labor: A Randomized Controlled Trial
SBC: Elm Tree Medical Inc. Topic: NICHDMeasurement of cervical dilation during late pregnancy and labor informs decisions in the management of labor and deliveryPrior published research suggests that practitioners are onlytoaccurate when judging cervical simulatorsWhen measuring laboring womentwo practitionersandaposmeasurements agree onlyof the timeDrEva Martin of Elm Tree Medical Incdeveloped a novel deviceDilaCheckto enable practiti ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Image Analysis Tools for mpMRI Prostate Cancer Diagnosis Using PI-RADS
SBC: ZMK Medical Technologies, Inc. Topic: 102ABSTRACTProstate cancerPCais one of the most commonly occurring forms of canceraccounting forof all cancer in menMulti parametric magnetic resonance imagingmpMRIhas led to improved capabilities for detectinglocalizingand staging PCaCombined with image guided prostate biopsympMRI has helped to improve diagnosis of clinically significant PCawhich helps to reduce mortality as well as unnecessary biop ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Innovative Nose-to-Brain Anticancer Drug Transport Facilitated by NEO100
SBC: NEONC TECHNOLOGIES INC Topic: 102Project Summary Abstract Many pharmaceutical agents are highly potentbut are unable to exert substantial therapeutic activity against disorders of the brainbecause the blood brain barrierBBBeffectively prevents their access to the site of intracerebral diseaseFor examplethe majority of glioblastoma patientsdespite the best efforts of current medical caredie within two years after diagnosisHencethe ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Protocol Feature Identification and Removal
SBC: P & J ROBINSON CORP Topic: N18AT018Protocols used for communication suffer bloat from a variety of sources, such as support for legacy features or rarely used (and unnecessary) functionality. Traditionally, the Navy subscribes to a blanket adoption of a standard protocol "as is". Unnecessary features are active and can be accessed by both internal and external systems creating security vulnerabilities. PJR Corporation's (PJR's) Pha ...
STTR Phase I 2018 Department of DefenseNavy -
Humanized EMAP II mAb as a Novel Therapy for Viral-Associated Lung Injury
SBC: Allinaire Therapeutics, LLC Topic: NHLBISummary Abstract The ultimate goal of this project is the validation of a humanized endothelial monocyteactivating protein IIEMAP IIneutralizing monoclonal antibodymAbfor progression to clinical evaluation as a novel treatment for patients with influenza associated lung injuryInfection with influenza virusIAVremains a major world wide health threat to high risk populations including the young and ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Embryonic stem cell high throughput screen accurately reports toxic stress
SBC: REPRODUCTIVE STRESS MEASUREMENT MECHANISMS & MANAGEMENT CORP Topic: NIEHSState of the art techniques in Developmental and Reproductive Technology use slowexpensive testing of pregnant female rodentsor of embryonic stem cellsESCsthat are cultured to lose stem cell qualities and differentiate into organ tissuesThis only produces toxicological outcomes similar to those in adult versions of these organsReproductive StressM has established high throughput screensHTSsthat te ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Interventions to Improve Reproductive Health among Adolescents
SBC: DFUSION INC. Topic: NICHDAlthoughyear olds are onlyof the U Ssexually active populationthey account for nearlyof themillion new cases of sexually transmitted infectionsSTIeach yearAlthough historically lowthe U Steen pregnancy rate continues to be one of the highest in the developed worldEvidence based prevention efforts can help avoid the costs and health consequences associated with STIs and unwanted teen pregnancy amon ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Optimization of Fatigue Test Signal Compression Using the Wavelet Transform
SBC: ATA ENGINEERING, INC. Topic: N18BT029Traditional approaches to accelerated fatigue testing rely on heuristic methods with thresholds based mostly on experience and engineering judgment. These methods generally do not apply to the multiaxial dynamic loading situations characteristic of most aerospace applications and often result in uncharacteristic fatigue damage and failure modes during testing. To overcome the limitations of tradit ...
STTR Phase I 2018 Department of DefenseNavy