Award Data

Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...

Cyber defense is difficult, but presents a particularly thorny problem for legacy systems, including legacy embedded systems, where in many such cases source code may not even be available. In this project, we proposed to investigate and extend a pattern-based approach recently developed by USC-ISI for analyzing and retrofitting binary code to protect against potential attacks. In this project, we ...

IFOS and STTR Partner Northwestern University propose to investigate the commercial viability of rapid transition of enhanced high-speed fiber-optic sensing systems. Fiber Bragg Grating (FBG) sensing based on Two Wave Mixing Interferometry (TWMI) in Photo-Refractive Crystals (PRC) has already been commercialized for dual-use applications. In this project, IFOS will leverage its experience as leadi ...

DESCRIPTION (provided by applicant): Current approaches to medical education produce new physicians with insufficient clinical competency to practice effectively with limited supervision, which has serious implications for patient outcomes during hospitaloff hours. Up to 70% of patients admitted to a hospital are admitted on nights or weekends, when staffing is low and residents may be in charge o ...

Under this STTR solicitation N20B-T028, the goal is to build on the strengths of HyPerComp’s development in the HDphysics suite of tools to meet NAVAIR’s requirements in solving large-scale problems in electromagnetics.  One area that will receive a major attention in this effort is the development of high order curved meshes for arbitrary geometries with small- and large-scale features that ...

Virtual EM is proposing a method to achieve orders of magnitude improvement in computational efficiency in full-wave CEM codes by using high-order curved elements. Virtual EM’s own commercial product VirAntenn™ will provide the CEM setting for both developing and implementing the new capability in Phase I and Phase II, respectively. Using multi-wavelength long cells with high-order basis forms ...

Quantum technology advances are currently at the forefront of U.S. military interest. In particular, recent developments in quantum communications have successfully demonstrated quantum key distribution (QKD) in space by the Chinese Micius satellite for quantum studies and quantum communication. Freedom Photonics is exploring photonic integrated circuit (PIC) solutions for time-bin QKD satellite a ...

Project Summary Natural products (NPs) and derivatives thereof provide a rich source of chemical matter for drug discovery and development. Over the past 30 years, NP-derived drugs have accounted for more than 35% of FDA approvals. Despite their demonstrated importance, development of new NPs has slowed over the past 15 years due to the lack of efficient methods for discovery, production, and opti ...

We propose to build a framework around an operator formulation to enable rapid development of massively parallel solutions to large graph problems. Graph algorithms are expressed by a small number of operators that are applied to components of the graph.

In hypersonic flight, airborne particles such as water or ice can penetrate and alter the bow shock and flow field, enhance erosion mechanisms and alter aerodynamics. Particles break up as they pass through the shock wave, impact the surface, erode and increase surface roughness, increase turbulence and heat transfer, and augment heating that can destroy heat shields prematurely. Many tests and th ...