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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NarcoBond: Opioid Targeted Biomimetic Nanosponges for Treatment of Opioid Overdose

    SBC: CiBots            Topic: NIDA

    Abstract We propose to develop a broad acute/sub-acute opioid drug detoxifying treatment for opioid overdose that can complement andamp; compensate for the deficiencies in nalaxone, using opioid-targeted biomimetic “nanosponges” that absorb overdosed opioids in the body. (Note: if this proof-of-concept is successful here, the approach may be tailored to other drugs-of-abuse.) Called “NarcoBo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Small Molecules MAP3K2/3 Inhibitor for Treatment of Acute Lung Injury

    SBC: QX Therapeutics, Inc.            Topic: NHLBI

    Project Summary Abstract Acute lung injuryALIor Acute Respiratory Acute Respiratory Distress SyndromeARDSare characterized by an increased permeability of the alveolar capillary barrier resulting in lung edema with protein rich fluidthus resulting in impairment of arterial oxygenationLung edemaendothelial and epithelial injury are accompanied by an influx of neutrophils into the interstitium and b ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Citizen-Science Technology for HealthyLiving at Home

    SBC: Access Sensor Technologies LLC            Topic: NIMHD

    Project Summary Environmental risk factors are attributable toof the chronic respiratory disease burden in the U Sand toof the burden from other non communicable diseasese gcancercardiovascular diseaseand diabetesExposure to environmental risk factors occurs through various forms of water and air pollutionwith a smaller attribution to sources like noiseradiationand physical hazardsMuch of this exp ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic antibodies for treating chemotherapy induced peripheral neuropathic pain

    SBC: ABALONE BIO, INC.            Topic: 102

    SummaryTherapeutic antibodies for treating chemotherapy induced peripheral neuropathic pain Chroniclife disrupting painsuch as allodynia from chemotherapy induced peripheral neuropathyCIPNis difficult to manageIn this Phase I SBIRAbalone Bio proposes to develop a first in class specific CBagonist antibody that is BOTH an effective and safe analgesic against CIPN as well as a co therapy to enable o ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A scalable system for high-throughput and longitudinal electrophysiology in rodent brain research

    SBC: SPIKEGADGETS, INC.            Topic: 101

    Psychiatric disorders give rise to aberrant patterns of activity within the complex neural circuits of our brains. Yet, the exact nature of these abnormal patterns is often unknown to developers of new treatments. The goal of this project is to enable circuit-oriented research of neuropsychiatric diseases using rodent disease models. The long-term objective is to catalyze the discovery of new ther ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A novel smartphone-based tool to quantify dual-task gait performance for concussion assessment

    SBC: Control One LLC            Topic: NINDS

    Project Summary Sport related concussions are a serious public health concern in the United Stateswithtomillion concussions reported annuallyYoung athletes who suffer a concussion experience quality of life alterationswith cognitive impairmentreduction in balance or coordinationand memory lossUnfortunatelyseveral factors limit the ability to accurately and feasibly evaluate the deleterious effects ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Highly accurate small-RNA sequencing of single cells (RealSeq-SC)

    SBC: REALSEQ BIOSCIENCES, INC.            Topic: 172

    Abstract The goal of this grant application is to develop the first commercially available library preparation kit for profiling small RNAs from single cells using NGS methods. Single-cell analyses of mRNA have allowed the identification of crucial differences between cells that were otherwise considered identical. These findings have shown that there is intrinsic “noise” in the regulation of ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Therapeutic in Situ Analgesic Implant for improved Oral-Facial Post-Operative Pain Outcomes

    SBC: Epigen Biosciences, Inc.            Topic: NIDCR

    PROJECT SUMMARY Analgesia for post operative populations remains a significant health need that calls for innovative therapies which improve both safety and outcome measuresRecent FDA drug safety warnings and studies focusing on post operative analgesia have highlighted the imperative need for new approaches that can be utilized for common clinical scenariosAccordinglynovel treatment options that ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Implantable Peripheral Nerve Stimulator for Treatment of Phantom Limb Pain

    SBC: RIPPLE LLC            Topic: 999

    Abstract Chronic phantom limb painPLPhas been reported to inflict as many asof people with amputationsPLP is described as feeling like burningtwistingitchingor pressure in part of the missing limbThese painful sensations have a substantial negative impact on quality of lifepeople who suffer PLP have high rates of depressiondifficulty sleepingregular absences from workdissociation with family frien ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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