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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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2-5A Antisense Targeting of Telomerase RNA
SBC: RIDGEWAY BIOSYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): The ribonucleoprotein complex telomerase has been implicated in the establishment and progression of many different types of tumors. Telomerase activity is detected in roughly 80 percent of all tumor cell types, but is absent in most normal cells. Thus, the disruption of telomerase activity is a particularly attractive means for treating multiple types of cance ...
STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
AAV-AIBP Therapy for Alzheimer's Disease
SBC: RAFT PHARMACEUTICALS LLC Topic: NIAPROJECT SUMMARY Therapy for Alzheimer’s disease and related dementias (AD/ADRD), slow-progressing neurodegenerative diseases, remains elusive. Therapeutic approaches focusing on beta amyloid (Aβ) removal from the brain or on targeting genes for which strong associations between their polymorphism and AD/ADRD are established, have had a mixed record of success. We propose a novel strategy to rev ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
A brief iPad-based screening measure for HIV-associated neurocognitive disorders
SBC: Digital Artefacts LLC Topic: NIMHDESCRIPTION (provided by applicant): HIV-associated neurocognitive disorders (HAND) remain prevalent despite effective anti-retroviral treatments. Cognitive impairments in the current treatment era are often mild and not readily detectable because currentscreening measures (e.g., the HIV Dementia Scale) lack sensitivity to detect subtle impairments in cognitive function. Although more sensitive t ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
A Cancer Vaccine for Ovarian and Breast Cancer
SBC: EPIMMUNE, INC. Topic: N/ADESCRIPTION (provided by applicant): The overall objective of this STTR program is to develop an effective cancer vaccine based on class II T cell epitopes derived from four tumor-associated antigens (TAAs) that are commonly over-expressed in ovary-and breast-derived tumors. The role of CD4+ T cell in eliciting an anti-tumor response is critical. The development of tumor specific CTL and the ge ...
STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health -
Accurate Prostate Cancer Diagnosis for Active Surveillance Patients Using a Novel
SBC: ProDevice Medical Supplies and Equipment LLC Topic: NCIProject Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A chemoenzymatic technology for the efficient synthesis of novel cryptophycins
SBC: ALLUVIUM BIOSCIENCES, INC. Topic: N/ADESCRIPTION (provided by applicant): The cryptophycins are a structurally diverse class of polyketide/non-ribosomal peptide natural products that possess potent anticancer activity. However, despite this impressive activity, the development of the cryptophycins into a beneficial cancer chemotherapeutic agent has suffered from clinically significant neurotoxicity that correlates with treatment. Non ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes
SBC: BIONIKS Topic: NIAMSDESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin
SBC: VAXIN INC. Topic: N/ADESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
A Compact, Cardiopulmonary Support Device
SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC. Topic: N/ADESCRIPTION (provided by applicant): The objective of this Phase I grant is to develop and test a compact cardiopulmonary support device (CCSD). This device pumps, transfers gas, and warms blood. The CCSD is attached to the patient via venovenous (VV) or v enoarterial (VA) cannulation and supplies respiratory support like extra-corporeal membrane oxygenation (ECMO) and pulsatile cardiac support si ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
Acoustic Device for Spine Surgery
SBC: SONOSCREW, INC. Topic: N/ADESCRIPTION (provided by applicant): An Acoustic Device for Preventing Spine Surgery Complications A specific and immediate concern arises in spine surgery, where an inserted instrument can damage the structures around the spine. For example, a device can be advanced too far into the vertebral body, and can cause damage to the nearby spinal cord and spinal nerve roots. These complications occur d ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health