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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of “Permit Wizard” Software for AssistedPermit Application Completion

    SBC: TOTAL QUALITY SYSTEMS, INC.            Topic: 833

    TECHNICAL ABSTRACT: The objective of this project is to research the technical feasibility of designing a software tool “Permit Wizard” that will automate the process for aquamarine permit application submittal, review, approval/disapproval and issue (including collection of fees). Aquaculture producers are currently faced with slow, complex, and often confusing permitting processes that must ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Topic 375: 18F PET Tracer For Imaging PD-L1 (Moonshot)

    SBC: SIBTECH, INC.            Topic: NCI

    New therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Noninvasive Prenatal Testing Platform for Aneuploidy at Five Weeks of Gestation

    SBC: Cradle Genomics, Inc.            Topic: NICHD

    The overall goal of this research is to provide a flexible prenatal genetic testing kit that can be expanded to detectany inheritable trait as early asand up toweeks of gestationfrom a safenoninvasive Pap smearStudiesshow that perinatal Pap tests pose no risk to mother or fetusand capture trophoblastlike cells that migrate fromtheplacentaintothereproductivetractTrophoblastretrievalandisolationfrom ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Targeting Exonuclease Resistant RNA to Develop Zika Virus Therapeutics

    SBC: Nymirum, Inc.            Topic: NIAID

    Project Summary Abstract Outbreaks of Zika VirusZIKVhave been recorded in Africathe AmericasAsiaand the Pacificand despite significant resources being dedicated to combat ZIKV proliferationthere is no known cureMany mosquitoborne flavivirus such as ZIKVDengue virusYellow Fever virusand West Nile virus have structuredUTRsStructured RNA elements in theUTRs allow the virus to resist degradation by ho ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Antimicrobial Intravascular Catheter Lock Solutions Based on Endogenous Nitric Oxide Release Agent

    SBC: NOTA Laboratories, Inc.            Topic: NIAID

    ! AbstractIntravascularIVcatheters in the hospital setting are associated with a high rate of bacterial colonizationresulting in andgtdeaths annually in the U Sfrom catheter related blood stream infectionsCR BSIsNewer commercial catheters pre loaded with silver or antibiotics within their walls have failed to dramatically reduce this very significant problemA variety of catheter lock solutionscath ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. An antigen-detection assay to diagnose Babesia microti infection

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    Project Summary Human babesiosis is a malaria like multisystem disease caused primarily by Babesia microtian emerging apicomplexan parasite that infects and develops within human erythrocytesThe parasite is transmitted to humans by the tick vector Ixodes scapularis and can also be introduced through blood transfusionInfection can cause flu like symptomsand severe infection can be fatalin particula ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells

    SBC: ISOPLEXIS CORPORATION            Topic: 172

    SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Non-Stigmatizing Hip Protection for Prevention of Fall-Related Injuries

    SBC: Alba-Technic, LLC            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hip fracture is one of the most serious fall related injuries in older adultshas a high rate of mortality and higher rate of disabilityThe incidence of hip fractures continues to increase as older adults become a larger proportion of the U SpopulationWithin one year post hip injuryof elderly die andof community dwellers are placed in nursing homesAccordinglyhip injury prev ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. The Home Evaluation, Assessment, Rating and Training of Gait (HEART-Gait) System for Monitoring Toe-Walking Severity in Children with Cerebral Palsy

    SBC: Veristride, Inc.            Topic: NLM

    Project SummaryCerebral PalsyCPis a group of disorders attributed to non progressive alterations occurring in the brain during fetal and newborn developmentThese alterations affect movementdevelopment and posturecausingsignificant lifetime functional limitationsCP is the most common motor disorder in childrenaffectingindividuals in the US aloneChildren with CP are commonly affected by gait impairm ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a hybrid transcatheter mitral valve replacement and repair device

    SBC: Dura LLC            Topic: NHLBI

    PROJECT SUMMARYMitral regurgitationMRis the most prevalent valvular heart disease in the U Saffecting approximatelyof the populationThere aremillion patients in the US with moderate to severe MR requiring treatmentHoweveronly approximatelypatients in the U Sundergo surgery for MR each year due to concerns about procedural complexity and patient safetyThere is great enthusiasm among the heart valve ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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