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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Minimally Invasive Cardiac Monitor for Neonatal and Pediatric ICU

    SBC: TRANSONIC SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently there exists no technology for routine measurement of cardiac output (CO) in neonates (0.4-2.5Kg) and low weight pediatric (2.5Kg+) patients in the intensive care unit (ICU). Accurate measurement of CO would a llow for better assessment of therapies and thereby improve patient health care. Conventional methods used with adults for routine CO measureme ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Novel PDE Inhibitors for Treatment of Cognitive Dysfunction in Schizophrenia

    SBC: INTRA-CELLULAR THERAPIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is submitted as a Phase II SBIR application, pursuant to our existing Phase I grant, which was funded in response to the NIMH Program Announcement #PA-02-027 entitled: "Pharmacological agents and drugs for mental disorders". The development of new pharmaceuticals for neuropsychiatric disorders is limited by the lack of rapid and effective methods ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Refanalin for lung preservation and transplantation

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Lung transplantation is the only effective treatment modality for patients with end-stage lung disease. Ischemia-reperfusion injury, associated with the retrieval, storage and transplantation of the lung is a major immu ne-independent factor adversely affecting early graft function, graft viability and recipient morbidity and mortality. Marginal donor lungs, ar ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Educational Television Program for Children of Immigrant Families

    SBC: Transcendent International, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The language barrier between immigrant parents and their English-dominant children is a pervasive and relatively unrecognized problem in an estimated 12 million U.S. households. This intergenerational language gap often leads to adverse health outcomes for both children and adults for the following reasons: (1) it hinders young children's ability to communicat ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. High Throughput in Vivo Drug Discovery- Phase II

    SBC: PGI HOLDING CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II application is being submitted in response to a continuing NIMH program announcement for Pharmacological Agents and Drugs for Mental Disorders. The goal of the proposal is to use an innovative behavior-dri ven approach to psychiatric drug discovery to overcome the major limitations associated with target-driven approaches that have impeded the dis ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Treatment of Surgical Sepsis with AM/AMBP-1

    SBC: THERASOURCE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR Phase II proposal is a plan to further develop a new therapeutic approach that will save the lives of patients with sepsis (especially surgical sepsis), a condition that affects 750,000 people every year in th e United States alone and also causes high mortality worldwide. Although activated protein C [APC, Drotrecogin alpha (activated), Xigris. marke ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Hypothermic Storage and Cryopreservation of Corneas

    SBC: CELL PRESERVATION SERVICES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Cell Preservation Services, Inc. (CPSI) is a biotechnology company dedicated to the development of novel technologies in the area of low temperature biology and medicine. CPSI's core molecular strategy is focused on und erstanding and manipulating the cell survival and cell death pathways that appear to be cell-specific and are activated as a consequence of low ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. SRF/MYOCD: new targets in Alzheimer's neurovasculature

    SBC: SOCRATECH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a multi-factorial neurodegenerative disorder. According to the prevailing amyloid cascade hypothesis, cognitive decline and distinct pathogenic features in AD relate to abnormal accumulation of amyloid beta-peptide (A?) in the brain. While efforts are underway to enhance A? clearance, prevent its formation, or to develop anti- A? sm ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Adolescent Drug Abuse Prevention for Youth Entering the Workplace

    SBC: NATIONAL HEALTH PROMOTION ASSOCIATES, INC            Topic: N/A

    ABSTRACT This Phase II SBIR application requests 36 months of support for the development and testing of a skill-based prevention program for career and technical education (CTE) students about to transition to full-time work. The program, LifeSkills Train ing Transition to Work (LST-TW), will [provide students with the self-management and interpersonal skills needed to resist internal and externa ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Microarray Chips for Rapid Detection of High Affinity Nucleic Acid Sequences.

    SBC: APTAMATRIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II project aims at further advancing and commercializing a microarray-based screening approach, for discovering nucleic acid probes that have high affinity and high specificity for protein and cellular target s. Oligonucleotides discovered in these screens can be engineered into sensors having exquisite sensitivity and selectivity for drug developmen ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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