Award Data

Project Summary Abstract An estimated million adults in the United States currently provide informal care to relatives and friends with Alzheimer s disease The economic contribution of informal caregivers service is estimated in the billions and is the cornerstone of care for the million people with the disease While informal caregivers undoubtedly perform an important role the respon ...

Despite the demonstrated benefit of CD targeted CAR T immunotherapeutics two challenges remain to bringing the therapeutics to market The first key challenge is to reproducibly manufacture the therapy so that the cellsandapos cytokine mediated function acts in a predictably consistent fashion post manufacturing The second key challenge is to manage the cellandapos s adverse effect immuno to ...

ABSTRACT Mechanical ventilation refers to the use of life support technology to perform the work of breathing for patients suffering from respiratory failure Patients undergoing mechanical ventilation are disproportionately older and suffer from multiple chronic conditions Approximately half of these patients are older than and half suffer from multiple chronic conditions Prolonged mechanic ...

Abstract Progress in the development of clinical cell transplantation therapy for Type Diabetes T D has been hindered due to the lack of patient specific inexhaustible human pancreatic islets that are immuno evasive Recent advances in stem cell differentiation have demonstrated the utility of human induced pluripotent stem cells hiPSCs as a valid cell source to produce patient specific ...

PROJECT SUMMARY ABSTRACT Introduction The Glove Rehabilitation Application for Stroke Patients GRASP Fast Track SBIR program will promote recovery of hand function following stroke through an instrumented orthosis that enables functional practice of manual tasks in fun and engaging activities within a virtual environment The effort combines patented sensor glove technology developed under the ...

Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

DESCRIPTION provided by applicant The EPA estimates that one out of every four Americans lives within three miles of a hazardous waste site Over brownfield sites are awaiting remediation and sites on the National Priorities List Potential Responsible Parties or the Superfund program are tasked with remediating these sites but insufficient funding and growing number of sites hav ...

Abstract Heart disease remains the leading cause of death in the US accounting for nearly of all deaths annually A high cholesterol level is a well known risk factor for heart disease Although blood cholesterol low density lipoprotein LDL C can be lowered using a number of marketed drugs only of patients taking these drugs are achieving the desired goals Furthermore patients with ...

Project Summary As United States healthcare seeks to address inconsistent quality and overwhelming cost data and technology have become central to all suggested approaches With newly available electronic health data and massive growth in processing power the hardest challenges in using clinical data are becoming clear Big data holds the potential to enable personalized patient care population ...

PROJECT SUMMARY This proposal aims to develop a therapeutic capable of preventing and treating the severe sinus inflammation associated with chronic rhinosinusitis CRS CRS is a debilitating inflammatory disease of the sinuses that impacts over million Americans and substantially diminishes the quality of life and productivity of affected patients From to the total US health care ...