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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of multimode vacuum ionization for use in medical diagnostics

    SBC: MSTM LLC            Topic: NIAID

    There is a critical need for rapid and cost-effective means for the detection of e.g. infectious diseases at an early stage, drug overdoses, and other health related testing necessities. Thus, significant commercial opportunities exist because of the lack of these capabilities as painfully “demonstrated” in the current pandemic. Mass spectrometry (MS), because of its ability to detect hundreds ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Amino Acids and Pediatric Hepatic Steatosis

    SBC: THE AMINO COMPANY LLC            Topic: 300

    7. Project Summary/Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in North America (1). Hepatic steatosis (HS) is the hallmark of NAFLD (2). NAFLD may transition in sub-groups to chronic inflammation (non- alcoholic steatohepatitis, NASH), and ultimately to cirrhosis. HS is prevalent in all stages of NAFLD. 3-10% of all children in the US and 40-70% of obese ch ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. PET Imaging of Damaging Neuroinflammation in Alzheimer's Disease

    SBC: EINSENCA INC.            Topic: NIA

    Alzheimer's disease (AD) is a devastating and progressive disease without a cure. Neuroinflammation is now recognized as a key early event in the development of AD. Aberrant neuroinflammatory response activates immune cells that can increase oxidative stress, and oxidative stress can directly damage neurons and axons, cause demyelination, and break down the blood-brain barrier (BBB). Thus, damagin ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Innovative Continuous Sanitization of Fresh Produce Harvesting Equipment

    SBC: En Solucion Inc            Topic: FDA

    Recent foodborne illness outbreaks traced to contaminated field harvesting equipment have highlighted the need for incorporating improved sanitization practices at the time of harvest. Field- harvested specialty crops represent 50% of the top ten foods linked to major recalls and outbreaks over the past five years. Proper sanitization of outdoor harvest equipment is made complicated by operational ...

    SBIR Phase I 2023 Department of Health and Human ServicesFood and Drug Administration
  5. Rapid Integration of Disparate Data Assets for Space Weather Research and Operations

    SBC: MEROXA INC            Topic: S14

    In Phase I, Meroxa proposes to demonstrate the technical feasibility of building accessible tooling and connectors (proof of concept) for NASA to move space weather data, regardless of format and location, to any destination in the format required and in real-time.

    SBIR Phase I 2023 National Aeronautics and Space Administration
  6. Solar Powered Rocket with Impulsive Thermal Engine (SPRITE)

    SBC: THERMASAT, INC.            Topic: Z8

    The Solar Powered Rocket with Impulsive Thermal Engine (SPRITE) combines the high performance of a nuclear thermal rocket with the simplicity of solar thermal propulsion. The system operates by collecting solar power and storing energy in a high temperature phase change material. This allows the SPRITE to minimize solar collector area by gathering energy over a period of time and releasing it quic ...

    SBIR Phase I 2023 National Aeronautics and Space Administration
  7. Lunar Extreme Water Container (LEWC)

    SBC: MOONPRINT SOLUTIONS LLC            Topic: Z13

    NASA is developing in situ water retrieval technologies to excavate regolith-based water deposits from various regions on the lunar surface, then transport, store, and process them into potable water, propellant, fuel cell reactants, and life support consumables for Artemis missions. Part of this logistics chain is a collapsible water container that can operate in harsh environments such as lunar ...

    SBIR Phase I 2023 National Aeronautics and Space Administration
  8. ARPA-H PHASE II SBIR AWARD, TOPIC 03- ROBOTICS FOR AUTONOMOUS SOFT TISSUE SURGERY TITLE: ADVANCED IMAGING AIDED AUTONOMOUS ROBOTIC CHOLECYSTECTOMY

    SBC: OPTOSURGICAL LLC            Topic: AH03

    This ARPA-H SBIR Phase II project aims to develop an 'autonomous' minimally invasive surgery approach, enhancing outcomes in procedures like laparoscopic cholecystectomy through advanced robotic tools and a 'smart' vision framework. The research team will explore whether the novel robotic platform can elevate the safety and efficiency of gallbladder removal surgery by integrating supervised autono ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. ARPA-H SBIR PHASE II TOPIC 4 FOR INTRA-OPERATIVE CONTRAST AGENTS

    SBC: OPTOSURGICAL LLC            Topic: AH04

    The project aims to advance the development of BL-760, a near-infrared contrast agent designed for clear intraoperative identification of bile ducts. This novel dye addresses the significant medical issue of bile duct injury during hepatobiliary surgeries (e.g., cholecystectomy, hepatectomy), impacting over 1 million patients annually. The project plans to produce BL-760 with high quality standard ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Live and Continuous Monitoring of Metal Cylinders and Tanks using Distributed Carbon Nanomaterial-based Sensing Networks

    SBC: MCET TECHNOLOGIES LLC            Topic: 22PH1

    This SBIR effort proposes using live and continuous monitoring of metal tanks, pressure vessels, and pipelines using carbon nanomaterial-based sensing skins to detect excessive physical strains, cracks, and to inspect impact damage. The proposed research and development work leverages 15+ years of fundamental research. The key objective is to advance the TRL level and the scalability of carbon nan ...

    SBIR Phase I 2022 Department of Transportation
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