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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Rapid detection of food borne pathogenic bacteria

    SBC: ALLIED INNOVATIVE SYSTEMS            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is to develop an ultrasound particle agglutination (UPA) method for determination of pathogenic bacteria Escherichia coli O157:H7 and Listeria monocytogenes in body fluids, food and envi

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Ultrasound monitored HIV rapid test

    SBC: ALLIED INNOVATIVE SYSTEMS            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is to demonstrate the feasibility of a novel method for detection of human immunodeficiency virus (HIV) antibody in the body fluids. The method is based on the use of ultrasound to signi

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Structural Signatures for Quality Control of Proteins

    SBC: ANALIZA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Higher-order structural information for biomolecules is an important component of quality control activities for recombinant proteins. Unfortunately, detailed structural information typically require highly complex

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Colonoscope Force Monitor

    SBC: ARTANN LABORATORIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Several million screening, diagnostic and therapeutic colonoscopies are performed each year in the U.S. hospitals and ambulatory surgery centers. The application of force to the colon and its anatomic attachments ca

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. In-vitro generation of cardiomyocytes from MAPC

    SBC: ATHERSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development and institution of stem cell and tissue engineering methodologies hold the potential to target many of the most significant cardiovascular diseases and have a dramatic impact on the treatment of one of

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Development of NFkappaB Inhibitors

    SBC: ATHERSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I proposal is to identify novel regulators of transcription factor NFkappaB. The products of this Phase I discovery program will be targets utilized in a Phase II campaign to develop of small mol

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Autologous cell therapy with SMC modified MAPCs

    SBC: ATHERSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of the current proposal is to establish genetic modification of Multipotent Adult Progenitor Cells (MAPCs) with Synthetic Microchromosome vectors (SMCs) as a strategy for application in autologous cell ba

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Small Molecular Inhibitors of Artemis as Radiosensitizer

    SBC: ATHERSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recent advances in our understanding of DNA repair mechanisms have led to the identification of the DNA repair specific nuclease, Artemis. Mutations in this enzyme do not affect viability, but enhance cellular sensitiv

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Probabilistic Engine for Virtual Screening

    SBC: BIOCOMPUTING GROUP INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this work is to provide a novel probabilistic computational engine for docking-based virtual screening. The engine is based on probabilistic model of Markov Random Fieds (MRF). MRF's have proven successful

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Divalent-Metal Chelating HIV-1 Integrase Inhibitor

    SBC: Bioflexis, Llc            Topic: N/A

    DESCRIPTION (provided by applicant): HIV makes three enzymes namely, Reverse Transcriptase (RT), Protease (PT) and Integrase (IN) like all retroviruses and these three enzymes were considered as effective targets for drug development. Currently people inf

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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