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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Multiplex ALEX-based Test for Protease Activity Profiling in Arthritic Joints

    SBC: CIRCULITE, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary Development towards treating small children and infants with mechanical circulatory support systems to bridge to transplant purposes is underway. However, implantable systems with miniaturized external components have delayed the process. To date, the need for mechanical circulatory support systems for infant and children with congenital and acq ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Glycoconjugate therapeutic peptides for improved treatment of human diseases

    SBC: CIRCULITE, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary Mechanical cardiac support has been shown to be an effective treatment in adults that suffer from congestive heart failure; however, there are limited options for treatment for the smallest of patientsthat present with heart failure. In the U.S., there are only two current options to treat infants (less than 10 kg), extracorporeal membrane oxyg ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Parallel Solid-State Electrodes for Turn-Key Intracellular Electrophysiology

    SBC: STEALTH BIOSCIENCES, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Interconnected networks of cells in the brain called neurons underlie all cognitive functions. Key advances in our understanding of brain function during the last several decades have resulted from technologies that permit monitoring of electrical activity in neurons. This technique, broadly referred to as electrophysiology, permits the study of circuits of con ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Attenuating reperfusion injury with combined hypothermia and gradual reperfusion.

    SBC: FOCALCOOL, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The primary care goal during a heart attack is to quickly restore blood perfusion. Reperfusion, however, is paradoxical, while it enables organ survival; it also enables destructive biochemical processes. While numerousadjunctive therapies for acute myocardial infarctions (AMI) have been studied, innovative combination therapies are needed. Both hypothermia and ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Administrative supplement to 5R44DA025375-03: Prescription drug abuse prevention

    SBC: WELLGEN, INC.            Topic: NCCAM

    DESCRIPTION (provided by applicant): Type 2 Diabetes (T2D) is an inflammatory disease affecting 26 million people in the US (11%) and is predicted to affect more than 30% of adults in the US by 2050. The economic cost of T2D is over 200 billion a year. People with T2D suffer from hyperglycemia due to low insulin production, poor transport of insulin, or cellular resistance to insulin which can l ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. High Yield Human Hepatocyte Isolation

    SBC: BIOINVENU CORPORATION            Topic: NIMH

    DESCRIPTION (provided by applicant): We plan to develop novel tools for assessing GPCR ligands modulating G-protein-dependent and ?-arrestin- dependent ERK signaling pathways. Many GPCRs display a phenomenon in which different ligands can differentially activate different signaling pathways via the same receptor. It has become clear that single signaling pathway approaches for identifying drug can ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a forced air add-on attachment for rocket stoves in Kenya capable

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    DESCRIPTION: Enhanced Membrane System for Supplying Quality Drinking Water Contaminants in Drinking Water: While many of the traditional waterborne diseases (cholera, typhoid) are now uncommon in the developed world, the continue to be a major cause of disease in developing countries and waterborne disease kills more people worldwide than all forms of violence. Waterborne disease outbreaks contin ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Implantable construct for architectural control of re-vascularization of ischemic

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    DESCRIPTION: Summary Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative Recent Events: On July 6, 2011 the United States Environmental Protection Agency (EPA) announced plans to establish new safeguards for hazardous secondary materialsrecycling with objectives to promote the economic, environmental, and public health benefits of recycling wastes, with an emphasis on several ind ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. IGF::OT::IGF Aerosolized Delivery of Anti-Tubercular Drugs

    SBC: NOSTRUM PHARMA            Topic: NIAID

    Develop an inexpensive, easy to use, aerosolized delivery system of a combination of anti-tubercular drugs that could be used for the treatment of multi-drug resistant tuberculosis (MDR TB ). PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. IGF::OT::IGF A Multiparticulate Dispersive Tablet for Pediatric Anti-TB

    SBC: Aucta Pharmaceuticals, LLC            Topic: NIAID

    To support the development of pediatric oral formulations for the anti-TB drugs isoniazid and streptomycin through various chemical processes. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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