Award Data

Because they seek out and bind only to specific cells, monoclonal antibodies represent a powerful method for selectively carrying radionuclides to cancerous cells. Current techniques for attaching radionuclides to monoclonal antibodies rely on metal ion chelates. These often lack sufficient stability, and the radionuclide may be released by in vivo chemical processes or by the compounds that enca ...

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Diabetic foot ulcers account for 55,000 amputations per year and are the leading cause of diabetic patient hospitalizations. Treatment requires off-weighting of the foot through bed rest, wheelchair, crutches, healing sandals, modified shoes, and/or bandaging treatments. Treatment compliance, however, is difficult to maintain since diabetics with peripheral neuropathy do not feel pain in the affec ...

Amino acid are the main components of proteins and are important elementary nutrients for living organisms. They are also valuable synthetic intermediates for the preparation of a large array of biologically active compounds important to the pharmaceutical industry. Examples of drugs based on amino acids are L-DOPA, L-tryptophan, and beta-lactam antibiotics. Unfortunately, typical production met ...

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"Creatv MicroTech proposes to develop high precision x-ray anti-scatter grids for medical imaging to improve image contrast of diseased tissue by reducing the detection of scattered x-rays produced by the imaging object. Some of the potential properties of the proposed anti-scatter grid are: (i) the grid pattern is two-dimensional, (ii) the vertical air-core opening is focused to a point x-ray sou ...

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