Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Novel Materials and Methods for Separations of Glycopeptides and Glycans

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION provided by applicant Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticated mass spectrometry Hydrophilic interaction liquid chromatography HILIC has great use in separations of glycopeptides and released glycans exhibitin ...

    SBIR Phase II 2013 Department of Health and Human Services
  2. Dynamic Frequency Passive Millimeter-Wave Radiometer Based on Optical Up-Conversion

    SBC: Phase Sensitive Innovations, Inc.            Topic: 941D

    In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

    SBIR Phase I 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Creating Spatial Disorientation in Flight Simulation

    SBC: Continuum Dynamics Inc            Topic: 122FA1

    Training in the symptoms of Spatial Disorientation (SD) has shown to be valuable in aiding pilots to recognize its onset and provide a means for mitigating its effects, but such demonstrations have traditionally been associated with specialized equipment and devices. Since the vast majority of pilots for the commercial aviation jet fleet are trained (or recertified) on 6-degree-of-freedom (DOF) h ...

    SBIR Phase I 2013 Department of Transportation
  4. Development of the Novel Small molecule drug Posiphen to treat Traumatic Brain In

    SBC: DIAMIR, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Alzheimer's Disease (AD) is the most common neurodegenerative disease: 5.4 million people are currently living with AD in the US, and up to 80 million Americans (over 55 years old) are considered to constitute the riskgroup for AD. In 2011, the annual cost of healthcare services for AD patients in the US reached 183 billion. There are currently no disease ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Administrative supplement to 5R44DA025375-03: Prescription drug abuse prevention

    SBC: WELLGEN, INC.            Topic: NCCAM

    DESCRIPTION (provided by applicant): Type 2 Diabetes (T2D) is an inflammatory disease affecting 26 million people in the US (11%) and is predicted to affect more than 30% of adults in the US by 2050. The economic cost of T2D is over 200 billion a year. People with T2D suffer from hyperglycemia due to low insulin production, poor transport of insulin, or cellular resistance to insulin which can l ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. NIH Phase II-UNCD as Bio-Inert Interface for Anti-Thrombogenicity Applications in

    SBC: Lucidicor Inc.            Topic: NCI

    DESCRIPTION: Protein kinases are chemically tractable drug targets, yet less than 5% of the human kinome has been thoroughly explored with selective small molecule inhibitors to demonstrate their therapeutic utility. Pharmaceutical companies are interested in evaluation of the therapeutic potential of targeting kinases to define new opportunities to address unmet medical needs. Lucidicor, Inc. h ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Novel Antithrombotic Diadenosine Tetraphosphate Analogs

    SBC: IMMUNOMEDICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The overall goal of this SBIR application is to initiate a clinical trial with a bispecific antibody (bsMAb) pretargeting procedure for detecting pancreatic carcinoma, based on a highly specific antibody (PAM4) recognizing an epitope found in pancreatic mucin. The pretargeting procedure has been shown pre-clinically and clinically to be highly sensitive and mo ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. CBT Supervisor's Toolkit: Phase II

    SBC: IMMUNOMEDICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Triple-negative breast cancer (TNBC) is a subset of breast cancers with poor prognosis and high mortality due to the lack of effective therapeutic regimens. This Phase I SBIR application is to develop E1-Rap, a novel immunoRNases, for treating TNBC. E1-Rap is a DOCK-AND-LOCKTM (DNLTM) complex, comprising four copies of ranpirnase (Rap) site-specifically tethere ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Riluzole Prodrugs for Melanoma and ALS

    SBC: LIGHT AGE, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Recent advances in photoacoustic tomography (PAT) have demonstrated its potential for 3D noninvasive high resolution imaging of soft tissues at penetration depths of many centimeters. Further, and perhaps even more importantly, imaging of tissue structure can be achieved while also providing crucial information regarding tissue composition and functionality. Th ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Development of a forced air add-on attachment for rocket stoves in Kenya capable

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    DESCRIPTION: Enhanced Membrane System for Supplying Quality Drinking Water Contaminants in Drinking Water: While many of the traditional waterborne diseases (cholera, typhoid) are now uncommon in the developed world, the continue to be a major cause of disease in developing countries and waterborne disease kills more people worldwide than all forms of violence. Waterborne disease outbreaks contin ...

    SBIR Phase I 2013 Department of Health and Human Services
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