You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. hANDY-i(TM): A non-invasive, dual-sensor handheld imager for intraoperative preservation of parathyroid glands

    SBC: OPTOSURGICAL, LLC            Topic: NIBIB

    Postsurgical hypoparathyroidism or hypocalcemia are known to frequently occur after allthyroid surgeries due to misidentification and/or accidental disruption of the bloodsupply to the healthy parathyroid glands. Such accidental removal or injury of theparathyroid glands may lead to complications that result in lifelong sequelae. Because of thesmall size, variable position, and similar appearance ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Novel small molecule HSP90 inhibitor for the management of atopic dermatitis

    SBC: Regranion, LLC            Topic: NIAMS

    PROJECT SUMMARY Atopic dermatitis/AD (or ‘atopic eczema’) is a complex, chronic, inflammatory skin disease that affects upwards of 35 million Americans. AD is characterized by a disruption of epidermal-barrier function, inflamed dry and thick skin, severe pruritus and significant impact on patients’ quality of life. Current standard of care involves topical emollients, avoidance of trigger f ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Dietary Quercetin to Treat Muscle Wasting Disorders

    SBC: AcePre, LLC            Topic: NCCIH

    PROJECT SUMMARY: Cachexia, the unintentional loss of body weight, is prevalent in chronic diseases and associated treatments. Cachexia is associated with reduced physical function, decreased tolerance for treatment, and increased mortality. Moreover, a cachexia diagnosis is consistent with a doubling in duration of hospital stay and an additional cost of $4,000/case compared to non-cachectic patie ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Automated, Drone-Based Grade Crossing Inspection

    SBC: VisioStack Inc.            Topic: 190FR6

    AXIS (Aerial Crossing Inspection System) is an innovative highway-rail grade crossing inspection system that uses UAVs, cloud processing and clustered-computing to perform inspections with unprecedented efficiency. AXIS is an end-to-end solution that preplans inspection flight paths, uses photogrammetry to create a 3D model of the crossing, calculates the crossing’s risk profile and generates de ...

    SBIR Phase II 2020 Department of Transportation
  5. Feasibility of expanding ischemia time for hearts destined for transplantation

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NHLBI

    In collaboration with Prof. Brandacher at Johns Hopkins University we plan to improve the currently most used clinical method of heart preservation, namely hypothermia at 0 to +4°C. We will build upon our base preservation formulation, Unisol™, that has been shown to preserved whole large animals below +10°C for 6- 8h after total blood replacement with Unisol™ with normal functions upon retu ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Evaluation of a Novel Therapeutic Approach to Treat Alcoholic Lung Syndrome

    SBC: FirstString Research, Inc            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT Twenty million people abuse alcohol in the United States and 1.8 million alcoholics are hospitalized every year. Alcoholic lung syndrome is recognized as a significant cause of morbidity and mortality amongst this large population, with estimated deaths approaching that of alcohol induced liver cirrhosis. Alcohol abuse induces persistent and profound oxidative stress in th ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Developing chemoenzymatic strategies, enzymes, and kits for accessible and affordable gangliosides

    SBC: Integrated Micro-Chromatography Systems, Inc.            Topic: 300

    Project Summary Gangliosides, analogous to biological antennae in cells, are involved in critical roles across multiple biological processes (i.e. pathogen infection, cell-cell communication, inflammation). Neuroprotective and neurorestorative functions of gangliosides have been explored for their therapeutic application in Parkinson’s disease and other neurodegenerative diseases. Despite such i ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets Abstract The critical importance of solid-state NMR (ssNMR) was recently demonstrated by, after nearly two decades of intense efforts, yielding the first atomic-resolution structures of the A40 and A42 amyloid fibrils that play a cru- cial role in Alzheimer’s Disease (AD). Key to that structure determination was a ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. A biophysical assay for RNA based resistance

    SBC: NUBAD, LLC            Topic: NIAID

    PROJECT SUMMARY The world is rapidly heading towards a pre-1940andapos;s scenario when it comes to fighting infectious disease. Antimicrobial resistance is a growing problem on a global scale, greatly hampering our abilities to quell worldwide epidemics such as tuberculosis and malaria, as well as the simple staphylococcus infection. The proposed project is significant because unless innovative st ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Autonomous Video Inspection System (AVIS)

    SBC: VisioStack Inc.            Topic: 20FR2

    AVIS (Autonomous Video Inspection System) is an innovative highway-rail grade crossing inspection system that will use deploy Artificial Intelligence based models with efficiency and accuracy. AVIS is an end-to-end solution that will evaluate forward-facing video to detect the presence and condition of key features that help improve the safety of pedestrians and vehicles at highway-rail crossings. ...

    SBIR Phase I 2020 Department of Transportation
US Flag An Official Website of the United States Government