Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Transformation of carbon emissions to high-value products through a two-step electrochemical platform

    SBC: LECTROLYST LLC            Topic: G

    Carbon dioxide utilization can help reduce carbon emissions, but gaps remain in the value chain from initial capture to high-value products. Lectrolyst LLC will develop an electrochemical platform centered on selective two-step conversion of CO2 to acetic acid and ethylene, to fill this need. Preliminary life cycle assessment and techno-economic analyses indicate ~200 million metric tons of CO2 em ...

    SBIR Phase I 2020 Department of EnergyARPA-E
  2. Transformation of carbon emissions to high-value products through a two-step electrochemical platform

    SBC: LECTROLYST LLC            Topic: G

    Carbon dioxide utilization can help reduce carbon emissions, but gaps remain in the value chain from initial capture to high-value products. Lectrolyst LLC will develop an electrochemical platform centered on selective two-step conversion of CO2 to acetic acid and ethylene, to fill this need. Preliminary life cycle assessment and techno-economic analyses indicate ~200 million metric tons of CO2 em ...

    SBIR Phase II 2020 Department of EnergyARPA-E
  3. Intelligent Biometrics to Optimize Prolonged Exposure Treatment for PTSD (IB-PE)

    SBC: Zeriscope, Inc.            Topic: 104

    PROJECT SUMMARY ABSTRACT Posttraumatic Stress DisorderPTSDis a debilitating disease affecting millions of American military veterans and civiliansProlonged ExposurePEtherapy is evidence based and effective but limited by high dropout rates and incomplete resolution of symptoms in approximately one third of patientsA crucial component of PEas well as interventions for anxiety disordersisIn Vivo Exp ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Ice-free vitrification and nanowarming of large osteochondral grafts for transplantation

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NIAMS

    Resurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis induced articular cartilage surface damageChondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantationWe have previously developed an ice free vitrification method ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Age-dependent Single-cell Metabolomic and Proteomic Profiling of Human Immune System

    SBC: IsoPlexis            Topic: NIA

    With this phase I submissionIsoPlexis proposes to deliver comprehensive profiling of the immune system as a measure of age dependent health in response to medical challenges or traumaThis assay will connect signaling events in the metabolome and proteome from thousands of single cells in parallel enabling the simultaneous tracking of metabolic activity and protein signaling within each immune cell ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Simulation Education for Ebola Healthcare Team Competency

    SBC: SIMTUNES            Topic: NCEZID

    Project Summary This product will keep healthcare workers prepared and safe in the next lethal viral pandemic through innovative simulation education Ebola and other deadly viral diseases represent a major threat to the nation and world At its peak in December Ebola had infected including in the U S and killed people including in the U S By the end of tragically healthcare workers had died Any hos ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Single-cell Phosphoprotein Assay to Evaluate Brain Tumor Therapeutic Resistance

    SBC: IsoPlexis            Topic: 102

    Although signal transduction inhibitors occasionally offer clinical benefit for cancer patientssignal flux emanating from oncogenes is often distributed through multiple pathwayspotentially underlying the resistance which causes failure of most such inhibitorsMeasuring signal flux through multiple pathwaysin response to signal transduction inhibitorsmay help uncover network interactions that contr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Universal Membrane Dehydrator for Dewatering Pharmaceutical Solvents

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 400

    Project Summary Specific AimThere are numerous needs in the pharmaceutical industry to use and recover high purity solventsKey uses includehigh purity alcohol for various applicationsthe ability to develop low cost dewatering of solvents and a relatively gentle and simple process for dewatering solvent under mild conditionsCompact Membrane SystemsCMSproposes a novel membrane process that can lead ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies

    SBC: IsoPlexis            Topic: NCI

    While CAR T therapies have advanced in the clinicthere are still two specific issues using these breakthrough therapies for blood cancersDurable responses in patients are only atand Cytokine Release Syndrome occurs inof treated patientsThese limitationsfor a drug that costs as much as $may cost an additional $for treating adverse events leading to caution for many clinical centers to administer th ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Multi-Omic Single-Cell System for Improved Combination Cancer Immunotherapy Monitoring and Implementation

    SBC: IsoPlexis            Topic: 102

    IsoPlexis proposes to deliver a novel multi omic method for targeted profiling of both the TCR sequence and proteome from an array ofsingle cellsSpecificallywe will deliver a single cellTCR sequencing and protein capture assay for identifying responsive antigen specific TCRsand concurrently evaluate these T cells for functional response to that antigenThe challenge remains to link the activation o ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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