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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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New approaches to kidney banking through nature-inspired high sub-zero preservation strategies
SBC: EXPANSE BIO LLC Topic: 400ABSTRACT The kidney transplant waitlist comprises 83% of the U.S. organ transplant waitlist. Yet, for every 5 patients who die or become too sick for transplantation, 3 kidneys are discarded. Organ preservation quality is linked to graft lifespan with kidneys having only 50% graft survival after 10 years. Extending preservation to a week, or longer, would enable nationwide (theoretically global) d ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
PET Imaging of Damaging Neuroinflammation in Alzheimer's Disease
SBC: EINSENCA INC. Topic: NIAAlzheimer's disease (AD) is a devastating and progressive disease without a cure. Neuroinflammation is now recognized as a key early event in the development of AD. Aberrant neuroinflammatory response activates immune cells that can increase oxidative stress, and oxidative stress can directly damage neurons and axons, cause demyelination, and break down the blood-brain barrier (BBB). Thus, damagin ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
AGR2-superantigen vaccine conjugate for the treatment of pancreaticductal adenocarcinoma
SBC: LEUKOGENE THERAPEUTICS INC Topic: 101Project Summary/Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer. Poor survival rates are largelydue to the late stage at which PDAC is diagnosed and a lack of effective targeted therapies. While the field ofimmunotherapy has significantly increased overall survival in some malignancies, they have not translated toPDAC. The long-term goal of this research pr ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Amino Acids and Pediatric Hepatic Steatosis
SBC: THE AMINO COMPANY LLC Topic: 3007. Project Summary/Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in North America (1). Hepatic steatosis (HS) is the hallmark of NAFLD (2). NAFLD may transition in sub-groups to chronic inflammation (non- alcoholic steatohepatitis, NASH), and ultimately to cirrhosis. HS is prevalent in all stages of NAFLD. 3-10% of all children in the US and 40-70% of obese ch ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets
SBC: DOTY SCIENTIFIC, INC. Topic: 400A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets Abstract The critical importance of solid-state NMR (ssNMR) was recently demonstrated by, after nearly two decades of intense efforts, yielding the first atomic-resolution structures of the A?40 and A?42 amyloid fibrils that play a crucial role in Alzheimer’s Disease (AD). Key to that structure determination was a techni ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Extended preservation of human livers: a nature inspired, high subzero controlled, limited freezing approach
SBC: SYLVATICA BIOTECH INC Topic: 300ABSTRACT 1 in 5 liver waitlist patients do not receive a new liver in time, while many more patients are never listed but could benefit from liver replacement. While “bridge-to-transplant” technologies (ventricular assist devices and dialysis) have transformed the outlook for heart failure and kidney failure, no such treatment exists for patients with liver failure. Current liver sharing limit ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Diagnosis of Neonatal Opioid Withdrawal Syndrome (NOWS) and development of a NOWS-App
SBC: PEDIALYDX INC. Topic: NICHDPROJECT SUMMARY PedialyDx Inc. proposes to replicate previous research findings and develop a commercial product that can assist in the diagnosis of Neonatal Opioid Withdrawal Syndrome (NOWS), the withdrawal that infants experience shortly after birth due to the abrupt discontinuation of fetal exposure to opioids. NOWS has become a significant public health problem, increasing from 1.6 per 1000 bi ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
hANDY-i(TM): A non-invasive, dual-sensor handheld imager for intraoperative preservation of parathyroid glands
SBC: OPTOSURGICAL LLC Topic: NIBIBAbstract Post-surgical hypoparathyroidism or hypocalcemia are known to occur frequently after thyroid surgeries due to the misidentification and/or accidental removal of healthy parathyroid glands. Approximately 150,000 thyroidectomies are performed in the US, 27% of these patients suffer from transient or permanent hypocalcemia, which can lead to lifelong sequelae and socioeconomic burden. Becaus ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Ototoxicity of modified aminoglycosides
SBC: NUBAD LLC Topic: NIAIDPROJECT SUMMARY Aminoglycosides are one of the cheapest and well-known antibiotics in clinical use for over 70 years, but one of the major limitations in their use is their ototoxicity. Although new generations of antibiotics have emerged in the last decades, aminoglycoside antibiotics maintain a leading role in treatment of acute infections and for specific indications such as tuberculosis or the ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Fully Autonomous Omnidirectional Adaptive Robots for the Disinfection and Decontamination of Transit Assets
SBC: ADVENT INNOVATIONS LTD CO Topic: 21FT1Public transit is particularly vulnerable to disruption and shocks from pandemics due to the collective nature of its mobility. The COVID-19 pandemic has brought new needs to keep all facilities clean for the safety of people at all times. To prevent the spread of coronavirus through transit facilities, keeping surfaces disinfected is incredibly important. The aim of this project is to contribute ...
SBIR Phase II 2022 Department of Transportation