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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 3770 results
  1. In-Field Magnetometry for Determination of Lithium Battery SOC

    SBC: TDA RESEARCH, INC.            Topic: 23PH3

    By 2030 the entire lithium-ion battery chain, from mining through recycling, is expected to reach a value of $400 billion and a market size of 4.7 TWh. LiB are used in personal electronic devices, e-bikes, tools, green-power storage and electric vehicles. Individual cells are commonly collected into packs or modules to provide the power required for automotive operation. The operational capability ...

    SBIR Phase I 2023 Department of Transportation
  2. A Low-Cost High-Capacity Portable Stormwater Treatment System for Emerging Contaminants

    SBC: TDA RESEARCH, INC.            Topic: 23FH1

    The State Departments of Transportation (DOTs) have limited right-of-way (ROW) to construct stormwater treatment controls. Hence innovative self-contained portable stormwater treatment systems are needed to reduce impacts on streams, and other waters; recreation facilities, and habitat by addressing emerging stormwater pollutants, particularly the suspended and dissolved pollutants from highway co ...

    SBIR Phase I 2023 Department of Transportation
  3. T-cell receptor mimic affinity reagent generation using an in vivo novel immunogen strategy

    SBC: ABBRATECH INC.            Topic: 300

    ABSTRACT Current therapeutic antibodies target the cell surface and within the external cellular environment. Yet intracellular proteins make up half of the proteome. Having a facile means of targeting those intracellular proteins for the generation of therapeutic antibodies would be highly desirable. Targeting MHC complexed with neoantigens from intracellular proteins would greatly allow the gene ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Augmented Reality Personalized Motion Tracking Assessment and Improvement Technology for Fall Prevention for the Spanish Speaking Hispanic/Latino Population in a Community Setting Using Mobile Phone

    SBC: KINIMA, INC.            Topic: NIA

    More than 1 in 4 people 65 and older fall each year, leading to more than $50 billion in annual spending for treatment. This cost is on an upward trajectory. We have less understanding of the impact of falls and risk in the Spanish-speaking Hispanic/Latino population. Although a variety of community-based public health programs are addressing fall prevention, these programs are in English and are ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Platform for the High Throughput Generation and Validation of Affinity Reagents

    SBC: ABBRATECH INC.            Topic: 300

    ABSTRACT We present a complete platform for the rapid generation and validation of recombinant mAbs. The innovations of this proposal include: (1) the pATHENA vector system for overnight conversion of phage display scFv or Fab clones into IgG molecules, (2) the Epivolve method for the isolation of site-specific Abs, (3) the incorporation of yeast display into pATHENA to allow biophysical measureme ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of TP-317 in Ulcerative Colitis

    SBC: Thetis Pharmaceuticals LLC            Topic: 300

    ABSTRACT Ulcerative colitis (UC) is a chronic, relapsing disease characterized by inflammation and ulceration of the colon and rectum that affects approximately 1.5 million people in the United States.1 Unfortunately, existing therapies have significant limitations. 5-ASA or mesalamine, which is approved as first-line therapy for UC, is effective in only 50% of UC patients and corticosteroids are ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Developing an integrated pipeline for routine generation of orthogonal GPCR-targeting nanobodies

    SBC: VITAN-BIOTECH LLC            Topic: 300

    Project SummaryA broad range of neurological indications, including schizophrenia, pain, Parkinson's and Alzheimer's diseases, and autism have been linked to G-protein coupled receptor proteins (GPCRs), making them attractive targets for therapy. Understanding GPCR dysfunction is essential for effective therapeutic development. However, deciphering the functions of GPCRs remains a daunting task in ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Pediatric Airway Trainer for Enhanced Clinical Education in Pediatric Critical Care

    SBC: TDA RESEARCH, INC.            Topic: NICHD

    Project Summary/Abstract Clinical training aids such as surgical mannequins and procedural trainers are important tools for teaching proper technique to physicians and first responders. However, the majority of these training tools were developed for adult anatomies. Pediatric patients are often more challenging to treat, but few resources exist for advanced simulation in pediatric critical care e ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Novel drug combinations for improving survival from acute radiation syndrome when administered 48 hours post- irradiation

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    Abstract. Bone marrow is one of the most radiation-sensitive tissues, and patients acutely exposed to total body irradiation (TBI) doses rt 2 Gy develop severe neutropenia, thrombocytopenia, anemia, and lymphopenia within days to weeks of exposure, often dying from infections (due to a lack of neutrophils) and uncontrolled bleeding (insufficient platelets) (referred to as the hematopoietic acute r ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. SensiTrak: Automated Assessment of Forelimb Sensation

    SBC: VULINTUS, INC            Topic: NINDS

    Project Abstract Current common methods for measuring somatosensory function in preclinical rodent models generally rely on withdrawal responses to uncomfortable or painful stimuli. These tests can be stressful to the animal, while also yielding a high variability in measured responses, and repetitive testing in longitudinal models may even result in chronic pain states. To better understand the c ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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