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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 375: 18F PET Tracer For Imaging PD-L1 (Moonshot)

    SBC: SIBTECH, INC.            Topic: NCI

    New therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. ALOFT: GPS RO from Balloons

    SBC: Atmospheric & Space Technology Research Associates, LLC (ASTRA)            Topic: 811

    TECHNICAL ABSTRACT: The NOAA Integrated Earth System Process and Predictions 2018 Subtopic 8.1.1 “Radio Occultation from Recoverable Air Balloons for Weather Applications” solicitation has the goal of demonstrating the feasibility of a hardware/software system for a balloon platform that has sufficient quality for measuring global navigation satellite system (GNSS) signals to enable retrieval ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Development of a Solar Powered Aerosol Reference Calibrator

    SBC: Access Sensor Technologies LLC            Topic: 813

    TECHNICAL ABSTRACT: This project will develop and demonstrate an inexpensive and portable calibration system for low-cost aerosol sensors. Current calibration methods are cost prohibitive and impractical for widespread field deployment. Access Sensor Technologies (AST) proposes to produce a solar powered aerosol reference calibrator (SPARC) that builds upon a established (patent pending) technolog ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Next Generation National Water Level Observation System

    SBC: Atmospheric & Space Technology Research Associates, L.L.C.            Topic: 8210

    TECHNICAL ABSTRACT: Accurate knowledge of water levels is crucial for day-to-day operations and planning of many US coastal activities. This information is used for the safe navigation of thousands of vessels on a daily basis, including passage of large vessels and cargos under and around coastal and river infrastructures. The NOAA Center for Operational Oceanographic Products and Services (COOPS) ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  5. The S0 UAS, and Air Deployed Solution for Boundary Layer Observations in Turbulent Environment

    SBC: Black Swift Technologies LLC            Topic: 8213

    TECHNICAL ABSTRACT: Previous efforts have demonstrated that targeted observations of tropical storms by UAS can provide extremely valuable data sets for improving forecasts and models, but are also difficult to obtain. A number of obstacles including regulations and the distance required to intercept evolving storms have limited the number of land based flights. The use of airborne deployed UAS ha ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Plasmid DNA positive control standards for molecular environmental assays

    SBC: Pisces Molecular LLC            Topic: 843

    TECHNICAL ABSTRACT: We believe that employing current molecular biology techniques it is possible to develop plasmid DNA based positive control standard kits for a wide variety molecular assays for environmental organisms, and that this represents a significant commercial opportunity. In Phase I we demonstrated that plasmid DNA-based qPCR positive controls are stable, perform as well as genomic DN ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Multichannel Commercial Cavity Ringdown Spectrometer for Oxides of Nitrogen and Ozone

    SBC: High Precision Devices, Inc.            Topic: 851

    TECHNICAL ABSTRACT: HPD, a small business focused on development and commercialization of advanced instruments, sensors and research equipment, proposes to partner with NAOA on technology transfer and commercialization of the NO(y) Cavity Ring-Down Spectrometer for atmospheric research. Since our founding in 1993, HPD has collaborated with researchers at NAOA and other government, commercial and a ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Position Error Maps for GPS/GNSS

    SBC: Atmospheric & Space Technology Research Associates, L.L.C.            Topic: 831

    TECHNICAL ABSTRACT: As our nation’s dependence on reliable satellite navigation systems for precise Position, Navigation and Timing (PNT) applications increases, any errors/uncertainties or degradation of service will have significant life, safety, and economic impacts. Ionospheric ‘space weather’ is one of the largest sources of error in PNT applications that use the Global Navigation Satel ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Supporting Healthy Aging with a Phytochemical Combination that Acts at Multiple Control Points in the Nrf Activation Pathway

    SBC: Pathways Bioscience, LLC            Topic: NIA

    The average lifespan and the number of older individuals is increasing in the US but because age is a primary risk factor for most chronic disease there is an accompanying increase in the burden of chronic disease in the US Diet and lifestyle choices including dietary supplementation may be useful approaches to slowing the aging process and increasing healthspan and also may be the best stra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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