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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel CO2 Gas Sensors for Autonomous Measurement of Ocean Carbon

    SBC: DIOXIDE MATERIALS, INC.            Topic: 82

    The objective of the proposed work is to determine whether Dioxide Materials' miniature C02 sensors have the potential to be adapted for autonomous measurement of ocean carbon. The existing sensors have many advantages for measurements of ocean carbon. They are much smaller and less costly than the existing sensors, work with much smaller gas samples, and use much less power. The sensors were d ...

    SBIR Phase I 2014 Department of CommerceNational Oceanic and Atmospheric Administration
  2. 120-X-2 Unmanned Aircraft System-Borne Atmospheric & Sea Surface Temperature (SST) Sensing

    SBC: PIASECKI AIRCRAFT CORP            Topic: 84

    To capture critical weather and SST data in the Tropical Cyclone Boundary Layer (TCBL), Piasecki Aircraft proposes to evaluate existing meteorological sensor packages, integrate new off-the-shelf MEMS sensors, and design an air-launched UAS to improve the resolution of observations captured in the TCBL. Capturing latent and sensible heat fluxes can be achieved reliably with a powered UAS (compare ...

    SBIR Phase I 2014 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Self-Contained Sub-Centimeter Positioning Platform

    SBC: TRUNAV LLC            Topic: 81

    The goal of this project is to develop, implement, and experimentally validate a new Differential Global Navigation Satellite System (DGNSS) capable of providing sub-centimeter positioning accuracy for quasi-static scientific, mapping, and survey applications. The main feature of the proposed DGNSS solution is that it leverages GNSS reference data from existing NOAA's Continuously Operational Ref ...

    SBIR Phase I 2014 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Hybrid Laser Arc Welding for Thick Plate High Performance Steels

    SBC: TECHKNOWSERV CORP            Topic: 132FH1

    High performance steels were developed in a cooperative program between the Federal Highway Administration (FHA), the American Iron and Steel Institute (AISI), and the U.S. Navy Carderock Division of the Naval Surface Warfare Center. HPS70W high strength steel is currently being used in bridge structures. HPS is stronger than conventional 70W steel and has less than 15% of the sulfur and 60% of th ...

    SBIR Phase I 2014 Department of Transportation
  5. Local Lymph Node Assay with IL-18 Endpoints

    SBC: MB RESEARCH LABORATORIES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The current industry standard for predicting contact dermal sensitization is the murine Local Lymph Node Assay (LLNA). A significant limitation of the LLNA is the frequency of false positives, as well as the occurrenceof false negatives. This limitation occurs as a result of the LLNA inability to always correctly distinguish between substances that are strongly ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Ubiquitin pathway inhibitors for treatment of asthma

    SBC: Progenra, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): Asthma is a chronic disease with considerable morbidity and no cures. Symptomatic treatment is efficacious but produces significant adverse effects. Thus, improved, targeted therapies for asthma are needed. Asthma develops when T cells (CD4+) differentiate to effector T cells, which secrete cytokines that assist in the recruitment and proliferation of various i ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Host-Targeted Mechanism of Action for Treatment of Seasonal and Pandemic Influenz

    SBC: EVRYS BIO LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Despite improvements in vaccine design, manufacture, and distribution, influenza A infection remains a significant public health concern. The February 2013 CDC Interim Adjusted Estimates of Seasonal Influenza Vaccine Effectiveness reported overall vaccine effectiveness of 56% and 67% against influenza A and B infections, respectively, with much reduced effect ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A New Generation of Botulinum Toxin Vaccines

    SBC: INVENTOX INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Botulinum toxin is one of the six categories of pathogens that have been designated as Category A Select Agents by the Centers for Disease Control. The toxin, which is generally acknowledged to be the most potent biological poison known, enters the body and acts on peripheral cholinergic nerve endings to cause paralysis of transmission. In seriously poisoned pa ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Single Antiviral to Treat Multiple Opportunistic Infections

    SBC: EVRYS BIO LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Transplant patients are quite susceptible to opportunistic viral infection resulting from immune suppression necessary for maintenance of their graft. In the case of renal transplant, 17,604 patients in 2011, a new graft means being taken off dialysis, improving quality of life and saving U.S. healthcare nearly 1 B annually. Therefore it is essential that the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Novel bispecific T cell engaging antibodies for treatment of Lyme disease

    SBC: ABZYME THERAPEUTICS LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Lyme disease (LD) is the most commonly reported tick-borne illness in the United States. According to the recent Center for Disease Control and Prevention report, approximately 300,000 Lyme cases are diagnosed each year. If left untreated, the infection spreads to joints, the heart and the nervous system. In most cases, infections and associated symptoms are el ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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