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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Discovery of inhibitors of Zika virus

    SBC: VENATORX PHARMACEUTICALS INC            Topic: NIAID

    PROJECT SUMMARY Novel inhibitors of Zika virusZIKVare urgently needed to prevent the occurrence of virus induced microcephaly and Guillain BarrsyndromeThe objective of this Phase I SBIR feasibility study is to identify drug like compounds that specifically inhibit ZIKV replicationDuring the course of this Phase I funding periodwe will execute hit finding campaign against a library ofcompounds with ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A low cost automated Gallium drug preparation device for diagnostic PET imaging

    SBC: Five Eleven Pharma Inc.            Topic: 102

    Abstract Five Eleven Pharma is developing a simple low cost device for automating the preparation of Ga labeled drugs at any site that is performing PET imaging The device is being developed to support the broader creation distribution research and use of Ga compounds in diagnostic PET imaging There has been a surge in the use of Ga based radiopharmaceuticals throughout the world in ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Assembled Porous Silica Membranes for Biomolecule SPE

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 400

    Abstract Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher efficiency sample preparation processes Sample preparation before high resolution analytical methods such as HPLC or LC MS can require effort and cost nearly equivalent to the actual sample analysis and data reduction Often sample preparation for proteomic glycoproteom ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Laboratory Bench Top EXAFS with STJ Spectrometer

    SBC: STAR CRYOELECTRONICS, LLC            Topic: 100

    Project Summary Extended X ray absorption fine structure EXAFS is a technique that gives element specific structural and chemical information about molecules EXAFS currently requires bright X ray beams from specialized synchrotron light sources for most samples and so its applications are limited by access to these facilities This project will involve improved X ray detectors based on superco ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of bioactive surface for pediatric hemodialysis catheters to prevent thrombogenic inflammatory and biofilm complications

    SBC: ENSION Inc            Topic: NICHD

    DESCRIPTION provided by applicant The most common hemodialysis catheter complications are thrombosis inflammation and biofilms Thrombotic deposition and inflammation have been shown to result in inadequate dialysis and lead to higher complication rates and increased mortality and can take many different forms including isolated clots thrombosis in vessels adjacent to the catheter tip or f ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Advances in contact lens materials to extend wear time for a new standard in vision correction and future medical devices

    SBC: INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC.            Topic: M

    PROJECT SUMMARY Over the last two decades the commercialization of silicone hydrogel andquot SiHyandquot composite technologies has led to new soft CLs that are more breathable comfortable and affordable including in daily disposable versions which have considerably broadened the customer base especially among younger generations Despite these improvements the major persistent problem fa ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Comprehensive Eye Evaluation Algorithm CEEvA

    SBC: VisionQuest Biomedical Inc            Topic: M

    Summary The objective of this project is to develop the Comprehensive Eye Evaluation Algorithm CEEvA a system to achieve blindness prevention in a cost effective way CEEvA uses fundus images and available personal medical data in the electronic medical record medical history and laboratory tests to automatically screen not only for DR but also for POAG and AMD in populations at higher risks ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. INHIBITORS OF THE PHD ZINC FINGER TO TREAT ANEMIA

    SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT Anemia is common disease and is associated with many conditions including end stage renal disease Recombinant versions of Erythropoeitin EPO the key hormone that regulates red blood cell mass have been a mainstay of treatment for this condition The necessity of parenteral administration however has prompted the search for alternative methods for increasing red ce ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Web based interactive program to prevent post partum depression in high risk women

    SBC: Fox Learning Systems, Inc.            Topic: 104

    Project Summary Postpartum depression PPD constitutes a general health problem occurring in of recently delivered mothers The impact of PPD is profound with considerable emotional pain for the mother as well as disturbances in infant development and later child adjustment Although the prevention of this disorder has garnered much attention few preventative interventions have demonstra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Vagus Nerve Stimulation Treatment for Asthmatic Bronchoconstriction

    SBC: ROSELLINI SCIENTIFIC, LLC            Topic: NHLBI

    Project Summary The Specific Aim of this proposal is to test the feasibility of using vagus nerve stimulation VNS for treating asthma related airway constriction that is refractory to current treatments There are approximately million people with asthma in the US About percent of these asthma sufferers experience early and late phase severe asthmatic bronchoconstriction that is refract ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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