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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of Manufacturing Technology for the Practical Application of Specialized and Environmentally Sensitive Nutrients, Enzymes, Immune-Stimulating Compounds and Biologics to Aquafeeds

    SBC: Zeigler Bros, Inc.            Topic: 823F

    In an effort to support the development of a domestic marine aquaculture industry, Zeigler Bros. Inc., (ZBI) proposes to continue its Phase I research by demonstrating the ability to scale up inclusion particle (IP) manufacturing. During Phase II ZBI will also demonstrate the efficacy of IOs for orally delivering phytase and probiotics to marine finfish. These efforts will directly address the p ...

    SBIR Phase II 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Advanced In-Shoe Orthotic Treatment for Foot Pain

    SBC: DIAPEDIA, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): This Phase II SBIR proposal describes a strategy and work plan for accelerating to market a new device that will provide an evidence-based, patient-specific solution to a significant public health problem: foot pain. The TrueContour(R) therapeutic insole system was originally conceived for prevention of forefoot injury in diabetes mellitus. We propose to furth ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Actuated Low-Force Biopsy Tool for Versatile Bone Lesion Access with Less Trauma

    SBC: ACTUATED MEDICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In this Phase II SBIR, Actuated Medical, Inc. will complete the development of the Actuated Low-Force Biopsy Tool for Versatile Bone Lesion Access with Less Trauma. Public Health Problem: Percutaneous bone biopsy is performed to obtain tissue for specific diagnosis of bone lesions identified through imaging or clinical evaluation. A major disadvantage of the ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Riluzole Prodrugs for Melanoma and ALS

    SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC.            Topic: NCI

    DESCRIPTION (provided by applicant): We have identified a novel Type IIb prodrug of riluzole, FC-311, which has the potential to revolutionize therapy for the treatment of the devastating condition of metastatic melanoma acting via a novel glutamatergic mechanism of action, and also be useful to treat amyotrophic lateral sclerosis (ALS) and the many other conditions for which riluzole itself is un ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Computed Optical Margin Assessment for Breast Cancer

    SBC: DIAGNOSTIC PHOTONICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Diagnostic Photonics, Inc. (DxP) is a medical device company developing an intraoperative imaging system for surgical guidance and real-time assessment of cancer tumor margins based on interferometric synthetic aperturemicroscopy (ISAM), a novel modality that uses light defraction to assess tissue. Because of the fatty nature of the breast, current intraoperati ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. COLORECTAL CANCER (CRC) SCREENING VIA RECTAL NANOCYTOLOGY

    SBC: NANOCYTOMICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this small business innovation research grant is to develop and commercialize a highly accurate, minimally invasive risk stratification technique for colorectal cancer (CRC) that is simple enough to be performed by the primary care provider during an annual physical exam. Although existing guidelines recommend CRC screening for all patients over age ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Algorithmic Acceleration and System Modeling for Low-Dose CT Imaging

    SBC: INSTARECON INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): With the increased use of x-ray CT, the development of a market for CT screening exams, and the imaging of younger patients, there is a growing concern about the public health risk caused by the radiation dose deliveredby x-ray CT. The reduction of this dose has therefore taken on increased importance, as evidenced by the recent NIH Summit on Managing Dose in C ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. E-Learning Assisted HAZWOPER Training for Medicolegal Death Investigators

    SBC: D&E TECHNICAL, INC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Human death investigations must by law be properly implemented even when the decedent is involved in or near to the scene of a hazardous materials emergency. This project intends to develop worker health and safety training for those staff of coroners and medical examiners who investigate deaths in hazardous materials environments. This innovative training will ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Surgical Adhesive for Seroma Prevention

    SBC: COHERA MEDICAL, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Seroma formation (fluid accumulation in the wound) is among the most common post-surgical complications, occurring in up to 50% of certain surgical procedures. TissuGlu(R) Surgical Adhesive is designed to adhere flaps of tissue and prevent the accumulation of fluid in surgical wounds, thereby reducing the need for drains and improving the time to recovery. Trad ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. NIH Phase II-UNCD as Bio-Inert Interface for Anti-Thrombogenicity Applications in

    SBC: Advanced Diamond TechNologies, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Artificial cardiovascular devices (ACDs) including ventricular assist devices (VADs) and mechanical heart valves (MHVs) have been implanted into millions of patients, to save or improve their lives. The increasing success of ACD implants has been accompanied with the unfortunate fact that these patients have to take powerful anticoagulant drugs and maintain a ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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