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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a blood test for breast cancer detection

    SBC: INTEGRATED TECHNOLOGIES AND SRVCS INTRNTL            Topic: N/A

    DESCRIPTION (provided by applicant): Mammography is the benchmark for breast disease detection and diagnosis. However, it can miss 10-15% of early stage breast cancers, and it is unable to distinguish between benign and malignant lesions with certainty. Av ailability of an alternate method e.g. biomarker based, which allows early detection/precise distinction between benign disease and breast canc ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. SUBCUTANEOUS MONITOR/ALARM FOR CARDIAC ARREST

    SBC: AJ MEDICAL DEVICES, INC.            Topic: N/A

    It is estimated that 220,000 people suffer cardiac arrest each year in the US, of whom only 10,000 survive to hospital discharge. The number of survivors could increase 10-fold if paramedical attention and/or defibrillation were available within a few min

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Sphingosine Kinase Inhibitors as Anti-Arthritis Agents

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Sphingolipids are being increasingly recognized as key mediators of inflammatory cascades of critical importance in multiple diseases, including rheumatoid arthritis and osteoarthritis. Most importantly, sphingosine 1-phosphate produced by sphingosine kinase (SK) mediates the effects of tumor necrosis factor-1 and interleukin-12, pro-inflammatory cytokines ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Radiopharmaceuticals for Imaging Brain Tau Pathology

    SBC: AVID RADIOPHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with more than 4.5 million Americans currently suffering from the disease. Clinical management of AD is complicated by lack of effective meth ods for early and accurate diagnosis of the disease. Thus, there is a significant unmet need for Alzheimer's disease diagnostic tools. The hypo ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. 18F-AV-133, A Novel Radiopharmaceutical for Differential Diagnosis of Dementia

    SBC: AVID RADIOPHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dementia, with its most prevalent subforms Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and vascular dementia, is a very substantial medical and societal problem. The emergence of many drugs and drug can didates that interfere with the disease mechanism of specific types of dementia makes it crucial to distinguish early between the various forms ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. 18F-AV-45 PET Imaging of Amyloid in PD with Cognitive Impairment

    SBC: AVID RADIOPHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dementia associated with PD (PDD) is common (affecting up to 80% of patients long-term) and highly disabling. Informative biomarkers are urgently needed to understand the pathology of PDD, to improve the early detection of cognitive deficits and to facilitate the development of treatments for PDD. Nuclear imaging technologies have the potential to produce such ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a non-invasive approach for early assessment of de novo 3MH production in cancer patients as a way of assessing which patients are at high risk for future developme nt of skeletal muscle atrophy. The approach is based on the known increase in the rate constant for de novo production of 3-methylhistidine (3M ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. A Non-Invasive Surrogate Test of OGTT to Screen for Pre-diabetes

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objectives of this proposal are to develop an inexpensive, totally non-invasive surrogate test for the 2-h oral glucose tolerance test (2-h OGTT) for the purpose of identifying individuals with pre-diabete s for preventive purposes. We believe that such a test can be developed based on oral administration of a 75-g 13C-labeled glucose solution adm ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Nanochannel Devices for High Throughput Single Molecule DNA mapping and Haplotypi

    SBC: BIONANOMATRIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long term objective of this proposal is to develop a fully integrated nanochannel chip and reader capable of single molecule mapping of linearized, long genomic material. The anticipated embodiment will permit dire ct visualization and analysis of megabase fragments of DNA extracted directly from a sample (possibly a single cell) with sub-kilobase resoluti ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Calcium phosphate-interferon (CaP-IFN) particles for pulmonary delivery of IFN

    SBC: BIOSANTE PHARMACEUTICALS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic infections with hepatitis B or hepatitis C viruses are global health problems affecting hundreds of millions of people worldwide. Various commercial products of interferon alpha are approved in the United States for the treatment of adults with hepatitis B and hepatitis C. However, therapy with interferon involves multiple weekly injections via intramu ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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