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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Sphingosine Kinase Inhibitors as Anti-Arthritis Agents

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Sphingolipids are being increasingly recognized as key mediators of inflammatory cascades of critical importance in multiple diseases, including rheumatoid arthritis and osteoarthritis. Most importantly, sphingosine 1-phosphate produced by sphingosine kinase (SK) mediates the effects of tumor necrosis factor-1 and interleukin-12, pro-inflammatory cytokines ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Durable Muscle-Prosthetic Bond for Artificial Tendons

    SBC: CARDIOENERGETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A coupling mechanism with the strength to fix a forcefully contracting muscle to a totally inert prosthesis, or to bone, would meet a serious and common need in clinical orthopaedics. We have explored a new approach t o such a coupling. The hypothesis was that a coupling prosthesis with a low-mass, high-surface configuration designed to transfer force by shea ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Wireless Movement Disorder Monitor

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective is to design, build, and clinically assess a Wireless Movement Disorder Monitor (WMDM) specifically tailored to Parkinson's disease (PD). Major PD symptoms that affect quality of life include tremor, bra

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Sprayable Surgical Adhesive for Seroma Prevention

    SBC: COHERA MEDICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this project is to create a sprayable surgical adhesive which would satisfy the surgical need for a strong, easy-to-use adhesive to adhere planar flaps of tissue. This novel adhesive will reduce fl uid accumulation after surgery by eliminating dead space in the wound and maintaining tissues in position for natural healing to occur. Seroma ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. CAD-CAM Technology for Diabetic Footwear

    SBC: DIAPEDIA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diabetes remains the leading cause of non-traumatic lower extremity amputations. Most amputations are preceded by a foot ulcer, so that successfully treating, or better still preventing, foot ulcers should reduce the n umber of diabetes related amputations. The majority of foot ulcers in diabetic patients are the result of loss of protective sensation (LOPS) s ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Biocompatible Coating for Pediatric Blood Oxygenators- Phase II

    SBC: ENSION Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Many oxygenators clinically available for pediatric (and adult) extracorporeal membrane oxygenation (ECMO) utilize heparin coatings such as Carmeda BioActive Surface on device surfaces, including the microporous hollow fibers, to improve biocompatibility. Despite application of these coatings, significant inflammatory and coagulation-related complications, as ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Web-based stroke education for patients and families

    SBC: Fox Learning Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Ischemic stroke is a major source of illness burden in the US. Stroke survivors are at high risk for recurrence and therefore they are an important group for secondary prevention. However, gaps in knowledge among stroke survivors, including inadequate knowledge of the early warning signs of stroke, inadequate understanding of the purpose and goals of rehabilit ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Not Available

    SBC: Fox Learning Systems, Inc.            Topic: N/A

    SUMMARYOF OBJECTIVES: 1. Develop a comprehensive curriculum of geriatric mental health education using Web-based interactive video documentary presentations. 2. Modify the presentations of each topic so that can be used to meet the educational needs of medical students, residents, as well as nursing, social work, pharmacy and psychology and will meet the requirements for CME and CE credits to prof ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Dry-reagent methods for detection of iodine in urine

    SBC: IBET, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long term goal of this project is to develop rapid, accurate and reliable methods and test kits for iodine determination in urine. The methods and test kits must be inexpensive and easy-to-use to perform determinati ons of iodine under field conditions. Dry-reagent test strip methods for detection of iodine in urine will be developed. The test strip method ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Video Rate Optical Coherence Tomography for Early Stage Cancer Visualization

    SBC: IMALUX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Bladder cancer is the 5th most expensive cancer in the US accounting for estimated $5.3 billion in direct medical costs in 2005. With bladder cancer patients having a 10 year survival rate of 77% and its known high rate of recurrence and progression, there is a need for the development of more sophisticated surveillance tools. Currently up to 6 random biopsies ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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