Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Microscopic Traffic Flow Simulation Models- An Open Source Approach

    SBC: New Global Systems for Intelligent Transportation Management            Topic: 081FH5

    PHASE II TECHNICAL OBJECTIVE The major objective of this Phase II proposal is to establish open source traffic simulation model and software, and to develop application programming interfaces to accommodate future traffic research needs. Objectives will be accomplished by building and demonstrating FOMM, an open source traffic simulation model and software. Furthermore, to accommodate future resea ...

    SBIR Phase II 2011 Department of Transportation
  2. Novel HBV Therapeutic with Potential for Treatment of Drug-Resistant Infection

    SBC: Pharmabridge, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): This is a Phase II proposal to advance development of disubstituted tetrahydro-triazolo-pyrimidines (TTPs) as specific inhibitors of hepatitis B virus surface antigen (HBsAg) secretion in chronic infection. High serum levels of HBsAg (antigenemia) are believed to underlie immunotolerance toward the infection. Although they are clinically beneficial, the current ...

    SBIR Phase II 2011 Department of Health and Human Services
  3. Bioadhesive Membrane Construct to Augment Tendon Repair

    SBC: KENSEY NASH CORPORATION            Topic: NIAMS

    DESCRIPTION (provided by applicant): The frequency with which tendon ruptures occur is increasing due to medical advances that allow an aging population to remain physically active longer than previously possible. There is a great deal of controversy in the orthopaedic community regarding the most effective way to treat such injuries. While progress has been made in improving the method of fixatio ...

    SBIR Phase II 2011 Department of Health and Human Services
  4. Chemoprotectants for Head-Neck Therapeutics

    SBC: REACTION BIOLOGY CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Chemoprotectants for Head-Neck Therapeutics Oral mucositis occurs as a major dose-limiting and complicating side effect of chemotherapy, radiotherapy, or combined chemo/radiotherapy. It is considered the most significant complication of head and neck cancer therapy. Oral mucositis is accompanied by tremendous pain and can cause life threatening complications. D ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Improved Dehydration Process for Pharmaceutical Synthesis II

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Compact Membrane Systems (CMS) proposes to develop a perfluoro membrane reactor technology that will provide a generally applicable tool for removing water and oxygen from pharmaceutical synthesis processes. This innovation aims to improve product quality and reduce manufacturing costs of pharmaceutical end products. Manufacturing cost reductions will be derive ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. Frontal Cerebral Hypothermia as a Treatment for Insomnia

    SBC: CEREVE, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The prevalence of insomnia ranges from 10-40% of the population in the United States (30 to 120 million people) with similar rates reported worldwide. Hypnotics are the primary medical treatment for insomnia, yet significant adverse events limit their use. Behavioral treatments for insomnia are effective, but the labor force and expense required to deliver ...

    SBIR Phase II 2011 Department of Health and Human Services
  7. Web-based Parent Training for Child Anxiety: Phase II

    SBC: WORKBOOK PUBLISHING, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Parents/guardians who are concerned about their child's emotional development, especially difficulties related to excessive anxiety and stress, are in a valuable position to serve as change-agents for their children. Unfortunately, they are typically unaware of when to try to help, or how best to help their children. This Phase II project aims to design, d ...

    SBIR Phase II 2011 Department of Health and Human Services
  8. New Drugs for Stress-related Affective Illness

    SBC: AZEVAN PHARMACEUTICALS INC            Topic: NIMH

    DESCRIPTION (provided by applicant): Vasopressin (AVP) antagonists represent a novel therapeutic class for the treatment of depression. The potential utility of these compounds has emerged from observations in depressed individuals, findings in animal models, and an understanding of changes in hypothalamic-pituitary-adrenal (HPA) axis regulation under chronic stress. This Fast Track proposal seeks ...

    SBIR Phase II 2011 Department of Health and Human Services
  9. Validation of ShuntCheck-Micro-Pumper, a non-invasive diagnostic procedure for de

    SBC: NeuroDx Development LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): This Phase 2 SBIR will provide and clinically validate the first portable, non-invasive diagnostic test for differentiating intermittently flowing patent shunts from occluded or partially occluded shunts - ShuntCheck- Micro-Pumper. This device will result in improved clinical management of hydrocephalus by providing a rapid and non-invasive method for detec ...

    SBIR Phase II 2011 Department of Health and Human Services
  10. On-line Ergonomics Solutions

    SBC: DAN MACLEOD, LLC            Topic: NIOSH

    DESCRIPTION (provided by applicant): The purpose of this project is to develop a website knowledgebase of ergonomics solutions to help reduce the risk factors for workplace Musculoskeletal Disorders (MSDs)* in general industry. Two ergonomics consulting businesses are involved: 1. Dan MacLeod LLC is a firm that specializes in working with employers in general industry to identify practical soluti ...

    SBIR Phase II 2011 Department of Health and Human Services
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