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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Individualized Fatigue Management Program Technology for Trucking Operations

    SBC: PULSAR INFORMATICS, INC.            Topic: 091FM1

    Individual differences in vulnerability to sleep loss and fatigue from extended work hours and night work are a substantial problem in transportation policy making, work schedule development, fatigue risk management strategies, and prediction of performance impairment in real-world operations (Van Dongen et al. 2003; Mollicone et al. 2010). Our group was the first to document the considerable magn ...

    SBIR Phase II 2012 Department of Transportation
  2. RAIL reduces variability and concentration of stress hormones in blood sampling

    SBC: ACTUATED MEDICAL, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In this Phase II SBIR, Actuated Medical, Inc. (f/k/a Piezo Resonance Innovations, Inc) will complete the development of the Resonance Assisted Insertion Lancet (RAIL ) System to reduce animal pain and stress response during laboratory animal blood sampling. Public Health Problem: Understanding the physiological and biological mechanisms of aging is the focus o ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Defining T cell epitopes in Dengue virus infection

    SBC: IMMUNOTOPE, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): There is a well-recognized need to develop vaccines that stimulates humoral immunity as well as a potent T cell immunity in order to achieve protection from infection with pathogens. Although numerous investigations arefocused on developing vaccines that induce protective humoral responses, only a few studies are aimed towards developing specific T cell immunit ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Portable electronically controlled transdermal patch for enfuvirtide delivery

    SBC: ACTUATED MEDICAL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): In this Phase II NIH SBIR, Piezo Resonance Innovations will further optimize and test the Portable Transdermal Patch (PTP) - a needle-free platform delivery technology for drugs and vaccines that are currently deliveredsubcutaneously. The portable, 200gm (7oz) electronically-controlled transdermal patch for Enfuvirtide delivery employs a patented transducer tec ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Small Antimicrobial Peptide Mimics as Drug-Resistant and Susceptib

    SBC: PolyMedix, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Malaria is a global disease causing gt 500 million clinical cases and gt 1 million deaths each year. Moreover, drug resistant Plasmodium falciparum has become a major problem. Therefore, it is crucial to discover new classes of drugs for anti-malarial drug design to combat resistant parasites. We propose that antimicrobial peptides (AMPs) may provide the basis ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. A novel fluorescent assay for ubiquitin isopeptide bond cleavage

    SBC: LIFESENSORS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): In the last decade there has been an explosive growth in the field of ubiquitin research, with approximately 530 human genes predicted to encode enzymes involved in the conjugation and deconjugation of ubiquitin. Of these 95 encode for deubiquitylases (DUBs). In order understand the biology of these enzymes better, there is a need for better assays to measure t ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Research and Deployment of a quantum mechanical NMR tool for fragment based drug

    SBC: QUANTUMBIO INC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Improving human health by enabling the development of drugs faster and cheaper is an important part of the NIH mission. This is partially achieved by introducing and constantly improving enabling technologies. One suchtechnology is structure based drug design. Determining the structure of a small molecule (drug candidate or lead compound) to a biological recept ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Modulators of HDL Metabolism

    SBC: SHIFA BIOMEDICAL CORPORATION            Topic: NHLBI

    Project Summary/Abstract Cardiovascular disease remains the leading cause of morbidity and mortality for both men and women, accounting for nearly 40% of annual deaths. High levels of LDL-C and low levels of HDL-C are well-known risk factors for heart disease. Although lowering low-density lipoprotein cholesterol (LDL-C) levels using a number of marketed drugs, of which statins are the leading dr ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Family-based HIV Prevention: An Interactive DVD

    SBC: Mee Productions, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): The overall aims of Phase I and Phase II of this SBIR project are to develop and refine an interactive DVD and workbook to reduce sexual risk behavior and substance use among urban black youth who are at high risk for contracting HIV by improving parent-adolescent communication, parental monitoring and the quality of parent/adolescent interactions. The final DV ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. Optimized Data Management Services (ODMS) for Tactical Environments

    SBC: DANIEL H WAGNER ASSOCIATES INC            Topic: OSD09SP2

    In this Phase II SBIR project, Daniel H. Wagner Associates will develop a full-scale prototype Optimized Data Management Services (ODMS) for Tactical Environments and its primary service oriented components: the Enterprise Information Acquisition Service (EIAS) and the Information Flow Optimization Services (IFOS). Our main goal is to transition CMA service oriented components into current and eme ...

    SBIR Phase II 2012 Department of DefenseNavy
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