Award Data

Piasecki Aircraft (PiAC) proposes to continue development and testing efforts of the Whimbrel UAS, a low cost, expendable, air-deployed weather survey unmanned aircraft system. The Whimbrel UAS, a low cost, expendable, air-deployed weather survey unmanned aircraft system. The Whimbrel USA has been developed to support the Tropical Cyclone Boundary Layer mission requirements and contains sensors an ...

This proposal leverages our current DOT-funded SBIR Phase II project developing software to assist truck drivers and companies to fatigue optimize driver scheduling and route planning. This project will build a set of web-services specially designed to provide objective quantitative feedback to truck drivers, dispatchers, and safety managers about fatigue from fatigue stressors common in trucking ...

Welding of HPS70W is well understood when using submerged arc welding (SAW) and shielded metal arc welding (SMAW) techniques. A Welding Advisory Group (WAG) which consisted of technical advisors from the Navy, AISI, and FHWA, major filler metal manufacturers, and steel producers determined the guidelines for welding HPS70W. As a result, comprehensive guidelines and welding procedures exist for SAW ...

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DESCRIPTION provided by applicant The smallpox virus variola has been responsible for the deaths of hundreds of millions of people worldwide Although smallpox was eradicated from the globe in following a valiant immunization campaign existing viral stocks may fall into the hands of those seeking to employ variola as a biological weapon This calls for the development of safe antiviral ...

DESCRIPTION provided by applicant Our long term goal is to provide a solution to the protein ligand binding affinity and pose prediction problems The protein ligand docking and scoring problem is one of the central problems in computational biology because of its importance in understanding intermolecular interactions and because of its practical payoff The transformative impact molecular do ...

DESCRIPTIONprovided by applicantHepatocellular carcinomaHCCis usually undetected until its later stageswhere theyear survival rate for patients is less thanHoweverthe survival rate can be as high asif the cancer is detected earlyUnfortunatelyearly detection of HCC is not possible with any screening tests that are currently availablesuch as ultrasound or imaging technologiesAlpha FetoproteinAFPwhic ...

DESCRIPTION provided by applicant Coronaviruses CoV are RNA viruses that cause gastrointestinal respiratory and neurological symptoms in several mammalian species The outbreak of the severe acute respiratory syndrome CoV SARS CoV in humans was fatal in of infected patients infecting people and killing The recent incidents involving the highly pathogenic Middle East ...

DESCRIPTION provided by applicant Barrettandapos s esophagus is a pre neoplastic disease that predisposes patients to development of esophageal adenocarcinoma EAC Approximately million people in the US have Barrettandapos s esophagus and they are frequently screened by endoscopy with pathological analyses of esophageal biopsies The goal of the screening is to detect premalignant changes e ...

DESCRIPTION provided by applicant Multiple myeloma MM is the second most common hematological malignancy in the United States and remains an incurable disease since nearly all MM patients will eventually relapse and develop resistance to currently available drugs Sphingolipid metabolism is being increasingly recognized as a key pathway in tumor biology In particular sphingosine kinases S ...