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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. SUBCUTANEOUS MONITOR/ALARM FOR CARDIAC ARREST

    SBC: AJ MEDICAL DEVICES, INC.            Topic: N/A

    It is estimated that 220,000 people suffer cardiac arrest each year in the US, of whom only 10,000 survive to hospital discharge. The number of survivors could increase 10-fold if paramedical attention and/or defibrillation were available within a few min

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Nitrogen Enriched Air for Fire Suppression

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Compact Membrane Systems (CMS) program is to develop a new platform technology for fire suppression and fire prevention systems around membrane supplied nitrogen enriched air (NEA). The limitation that the atmospheres used in the fire suppression be breathable to occupants in the proximity of a fire is easily accomplished by CMS technolog ...

    SBIR Phase II 2008 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. Industrial Metabolic Engineering

    SBC: FERMALOGIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Industrial metabolic engineering is a method for performing strain improvement in industrial microorganisms by harnessing the power of random in vitro transposition mutagenesis. The organisms we aim to improve in this s tudy are the actinomycetes, a group of soil bacteria that are best known for their ability to produce over two thirds of the worlds naturally d ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. HIFU and Immunotherapy Treatment of Metastatic Prostate Cancer

    SBC: FOCUS SURGERY INC            Topic: N/A

    DESCRIPTION (provided by applicant): Experimental investigations have demonstrated that the delivery of HIFU (High Intensity Focused Ultrasound) to cancerous tumors results in the release of heat shock proteins and generates a beneficial immune response. T he release of proteins into the blood as a result of HIFU therapy is further demonstrated by the spike of the serum prostate specific antigen ( ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. High Efficiency X-ray Fluorescence Detectors

    SBC: HD TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): It has been repeatedly emphasized in various reports and workshops [1-2] that the development of better X- ray fluorescence detector systems is urgently needed to solve the saturation problems with the currently availab le detectors. The multilayer analyzer array detector (MAAD) using linearly graded multilayers has been successfully developed to handle the lar ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Hardware for Ultra-Fast CT Reconstruction

    SBC: INSTARECON INC            Topic: N/A

    DESCRIPTION (provided by applicant): Image reconstruction in x-ray computer tomography (CT) scanners lags far behind the data acquisition. For example a whole-body scan using the latest 64-slice medical CT scanners, with sub-millimeter slice thickness, wh ich takes about 10 seconds to acquire, requires about 20 times as long to reconstruct. This computational lag occurs despite the use of expensi ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. CT Dose Reduction by Fast Iterative Algorithms

    SBC: INSTARECON INC            Topic: N/A

    DESCRIPTION (provided by applicant): With the increased use of x-ray CT, the development of a market for CT screening exams, and the imaging of younger patients, there is a growing concern about the public health risk caused by the radiation dose delivered by x-ray CT. The reduction of this dose has therefore taken on increased importance. The objective of this work is to develop a novel computat ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Extracting Semantic Knowledge from Clinical Reports

    SBC: LOGICAL SEMANTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Analyzing and processing free-text medical reports for data mining and clinical data interchange is one of the most challenging problems in medical informatics, yet it is crucial for continued research advances and impr ovements in clinical care. Natural language processing (NLP) is an important enabling technology, but has been held back because it is difficul ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. A new cancer protein solubility tool: Entropic Bristle

    SBC: Molecular Kinetics Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Expression and purification of cancer-associated proteins are prerequisite steps necessary to study their functions, structures, and interactions. However, these steps are often challenging or even infeasible due to poo r protein solubility. This project seeks to develop a tool, a set of entropic bristle-based AquoProtTM vectors, to dramatically increase the fr ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Obese diabetic (type II) rat model without leptin/leptin-receptor defects

    SBC: PRECLINOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): An estimated 18.2 million people (6.3 percent of the population) in the United States have diabetes; 90 to 95 percent of all diagnosed cases are type II diabetes (NIDDK, 2005). The search for new and more effective ther apies to address the growing number of Americans with type II diabetes and related conditions is currently hindered by the lack of a research a ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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