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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The great need for more efficient and effective oncologic drug development has driven the discovery and integration of biomarkers into all phases of clinical research. Further still, biomarkers are entering the clinical arena as early means of determining which patients are likely benefiting from a particular drug. One field of targeted therapy that has relied ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years of age have at least moderate periodontitis with over a quarter having lost their teeth, resulting in serious health a nd quality of life repercussions. Bone grafting is routinely necessary prior to the placement of Dental implants due to bone loss caused by per ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Point of Care Attachment of Antibiotics onto Metal Implants

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio ns, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significa ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Click Chemistry for Immobilized Bone Morphogenetic Protein

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Growth factors are potent signaling molecules, initiating essential cellular programs for differentiation, proliferation and survival. Only recently have large molecules like growth factors, been employed to enhance the efficacy and specificity of medical implant therapies. In particular, procedures that require native tissues to interact with an implanted mat ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Electrochemical Enzyme Immunoassay to Test Blood HBV

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant):Millions of Americans are infected by the hepatitis B virus (HBV)-many of whom have no reason to believe they are infected. There is a need to track down America's millions of HBV victims-as well as a corresponding need for innovative technology to test blood for HBV. HBV is clearly a national medical priority. ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  6. New Single Nucleotide Polymorphism (SNP) Scoring System

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Identifying the roles of variable individual genetic factors can revolutionize approaches to the diagnosis, treatment, and prevention of human disease. Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations that affect human health, and better methods for scoring known SNPs in the human popul ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Innovative Tools for the Molecular Diagnosis of Cancer

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Cancer Institute has called for new tools for cancer research and diagnosis that are accurate, practical and affordable. Alderon Biosciences, Inc. proposes to fill this need by developing an open biosensor platform technology for quantitative studies of cancer gene expression, with the goal of replacing slower and more costly methods. The working ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Composite Metal/Ceramic Bearings for THA Implants

    SBC: SINTX TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (Provided by Applicant): The implications of developing materials with enhanced fracture toughness, damage resistance, reliability and ultra low wear is of significant interest to the orthopedic community, since it directly addresses a vital clinical concern- eliminating wear debris mediated THA implant failures. In Phase I we made a significant ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  9. N/A

    SBC: APOLLO LIGHT SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  10. USE OF ADIPOSE-DERIVED PREADIPOCYTES IN BONE DISOREDERS

    SBC: ARTECEL SCIENCES, INC.            Topic: N/A

    Non-healing bone fractures and periodontal bone loss constitute significant clinical problems with few approved medical options. Bone repair is enhanced by the presence of osteoblasts or osteoblastic precursor cells. Subcutaneous adipose tissue is a plentiful, accessible, and replenishable source of human stromal cells for transplantation. In Phase I of this SBIR, we tested the hypothesis that hum ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
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