Award Data

RESEARCH WILL BE CONDUCTED INTO OPTICAL FIBER-COUPLED FLUORESCENT SENSORS FOR THE CONTINUOUS IN VIVO MONITORING OF BLOOD GASES. THE PURPOSE OF PHASE I IS TO IDENTIFY FLUORESCENT CHEMICAL SYSTEMS SPECIFICALLY SENSITIVE TO PH, PO2, PCO2, AND TEMPERATURE. FROM THESE IDENTIFIED SYSTEMS, A SELECTION WILL BE MADE OF THOSE COMPATIBLE FOR USE IN A MIXED SENSOR PROBE. THE GOAL OF THIS STUDY IS TO MINIMIZE ...

DESCRIPTION (provided by applicant): We have recently demonstrated that alpha-hemolysin produced by S. aureus plays a key role in the pathogenesis of staphylococcal pneumonia, and identified beta-cyclodextrin derivatives that potently inhibit the cytotoxic effects of this secreted bacterial toxin. The overall goal of this feasibility study is to examine the ability of these inhibitors to provide i ...

DESCRIPTION (provided by applicant): The Cells and Surveys report (National Research Council 2000) reports that collecting biological information dramatically improves the value of household surveys by adding a rich dataset of information to longitudinal databases that is not collected today. In fact, since the Cells and Surveys report the collection of biological data and performance measures (in ...

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AMERICAN RESOURCES CORPORATION PROPOSES TO ASSIST THE OFFICE OF HUMAN DEVELOPMENT SERVICES IN THE REMOVAL OF BARRIERS TO EMPLOYMENT OF THE DEVELOPMENTALLY DISABLED (DD). AT THE CONCLUSION OF THE PROPOSED PROJECT, HDS AND INVENTORS OF DEVICES TO ASSIST THE DD POPULATION WILL HAVE ACCESS TO A COMPUTER DATA BANK WHICH WILL IDENTIFY THE DD POPULATION WHICH WOULD BENEFIT FROM A PARTICULAR DEVICE. THE S ...

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DESCRIPTION (provided by applicant): The overall goal of this multi-phase SBIR research effort is to develop a handheld fall risk assessment instrument for use by health and elder care providers. Falls occur in up to 30% of those over the age of 65 and up to 40% for people over the age of 80. Falls place each individual at risk for dangerous closed head injury and long bone fractures. The mortalit ...

DESCRIPTION (provided by applicant): Recent advances in the size and performance of micro-electromechanical systems (MEMS)-based inertial instruments enable the development of a balance prosthesis to provide feedback regarding head orientation to patients with chronic balance dysfunction. There is a need for balance prostheses to assist patients with such chronic balance disorders, as well for dev ...

DESCRIPTION (provided by applicant): This SBIR Phase I application addresses the development of an integrated, multi-purpose Sleep and Physical Activity Recording and Technical Analysis (SPARTA) system that can be used to independently assess both sleep (duration, quality, and timing) and physical activity (duration, frequency, intensity, and timing). As an objective monitor for the study of sleep ...

DESCRIPTION (provided by applicant): The majority of elders prefer to lead an independent lifestyle, with a minimum of caregiver intervention. Many seniors, however, are frail and suffer from imbalance as a result of their health status; they are at risk for falls and would benefit from having some type of safety net in place. Studies have shown that half of elderly fallers have problems getting ...