Award Data

DESCRIPTION (provided by applicant): Methadone is an important long-term maintenance therapy for drug addiction and currently is frequently used for analgesia. However, methadone prolongs the QT interval on the electrocardiogram and this increases risk for life threatening arrhythmias and has led to the FDA's placing a black box warning on methadone's label. Initial studies in our laboratory hav ...

DESCRIPTION (provided by applicant): This SBIR Phase I project will create an online Career Simulation development Environment (CSE) for biomedical and behavioral science careers. The Phase I project will deliver an engaging, interactive, exploratory, and constructivist simulation of an alcohol abuse career. It is estimated that there are 11 million underage drinkers in the United States (O*NET). ...

City planners and engineers need detailed assessments of public rights-of-way to evaluate existing conditions, determine compliance with draft accessibility guidelines, and plan reconstruction projects. Current assessment methods are inadequate and inefficient due to the time and resources required. This project will develop an automated public rights-of-way assessment process and the measuremen ...

DESCRIPTION (provided by applicant): Cancer symptoms due to disease progression or side effects caused by cancer treatment are prevalent. Most cancer patients are treated in outpatient settings, having to self-manage these symptoms at home. For a variety of reasons, symptom self-management by patients and their caregivers can be a tremendous burden on themselves, resulting in suboptimal patient ou ...

DESCRIPTION (provided by applicant): Our ultimate project goal is to develop a patient-reported outcomes (PRO) management system specifically designed to address the functional limitations experienced by people with physical and neurocognitive disabilities. We recognize that there are many clinical conditions that could cause these functional impairments, but intend to demonstrate the technical fe ...

DESCRIPTION (provided by applicant): Low levels of high-density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart disease (CHD). HDL cholesterol levels are predictive of major cardiovascular events in patients treated with statins. This relationship was also observed among patients with LDL cholesterol levels below 70 mg per deciliter. Studies have demonstrated that poly ...

DESCRIPTION (provided by applicant): The goal of this project is to create an intuitive control scheme for rotation of a prosthetic joint that preserves proprioception of limb rotation. Such a control scheme would reduce the cognitive burden of controlling the prosthetic limb and allow the incorporation of additional prosthesis movements, thus reducing the burden of disability. This project seeks ...

DESCRIPTION (provided by applicant): Compact Membrane Systems, Inc. proposes to develop novel blood oxygenator membranes with enhanced blood biocompatibility. These will be used to enhance conventional cardio bypass surgery minimizing post operative effects. In addition, they will provide a key element for long term blood oxygenation associated with extracorporeal membrane oxygenation, acute respi ...

DESCRIPTION (provided by applicant): The overall objective of the proposed research is to develop and validate a hearing screening instrument for use in occupational health. This instrument will combine information about an individual's functional hearing ability as determined from HINT thresholds, with acoustic information about the noise environments where hearing-critical tasks occur. These ...

DESCRIPTION (provided by applicant): ImmersiveTouch, Inc. (Westmont, Illinois) is a small business that develops fully immersive, visio-haptic virtual reality software engineered into a hardware workstation for the training of surgical residents. This workstation, the Company's simulator seeks to provide residents with the repeated, deliberate virtual reality practice that will give them skill ...