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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A single-cell device to capture and analyze rare T-cells from solid tumors.

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    Checkpoint inhibitors towards targets such as PDand PD Lare being developed to activate quiescent T cells embedded in tumors and enable them to recruit the rest of the immune system to fight a cancer massHow these new cures reactivate the relatively few Tumor Infiltrating LymphocytesTILsenabling the release of a complex message of cytokines to recruit the immune systemthus impacting treatment effi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Precision quality check of immunotherapeutics via single-cell cytokine mapping

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    Adoptive transfer of autologous T cells engineered to express chimeric antigen receptorsCARshas emerged as a promising immunotherapy for patients with hematologic malignanciessuch as CDCARs in leukemias and lymphomasHoweverchallenges remain in terms of manufacturing consistency and the functional profile of the CAR T cell productsince infused cellsasliving drugscan be activated and release a varie ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A single-cell mouse proteomic system to accelerate pre-clinical immune therapeutics

    SBC: ISOPLEXIS CORPORATION            Topic: 100

    With this PhasesubmissionIsoPlexis proposes to deliver a single cell proteomic solution for ultra sensitive detection of unique correlative biomarkers in pre clinical mouse modelsin an automated system that can be used to accelerate the discovery of potential immune therapeuticsThe recent revolution in new basic science discovery is failing to translate into improved patient treatmentThe reduction ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Single-Cell Device to Detect Pathogenic Cell Populations in Bone Marrow Disease

    SBC: ISOPLEXIS CORPORATION            Topic: NIBIB

    MyelofibrosisMFbelongs to a group of closely related chronic blood diseasesmyeloproliferative disordersMPDMost MF patients have no symptoms or present with nonspecific constitutional symptomsweight lossfatigueas such an early stage diagnosis of MF is challengingMF is clinically suspected when patients present with an enlarged spleen and or with anemiathrombocytopeniaor leukopenia leukocytosishowev ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Printable Materials with Embedded Electronics and Radio Frequency Components

    SBC: Delux Advanced Manufacturing, LLC            Topic: A16006

    To reduce size, weight, power and cost (SWaP-c), military platforms have been evolving towards a more integrated design approach that efficiently utilizes all available space. In fact, to accommodate limited space constraints many commercial off-the-shelf (COTS) systems will need to be replaced by custom designed and fabricated components. For radiofrequency (RF) electronic systems, this will requ ...

    SBIR Phase II 2017 Department of DefenseArmy
  6. Tools for Cross-Platform Software Development and Performance Projection

    SBC: EM PHOTONICS INC            Topic: AF161088

    Developers of modern software, particularly those targeting mobile or embedded platforms, are presented with a wide variety of hardware choices. Solutions can be built on microprocessors (e.g. x86, ARM, or Power architecture), GPUs (e.g. NVIDIAs Tegra), DSPs, FPGAs, or some combination of these technologies. Not only does this place a significant burden on programmers in understanding the intricac ...

    SBIR Phase II 2017 Department of DefenseAir Force
  7. Advance Brake Fade Warning System and Test for Wheeled Vehicles

    SBC: HODGES TRANSPORTATION, INC.            Topic: A15072

    Mountain descent test procedures that replicate conditions found in severe mountain environments are essential in identifying the limitations of current and future vehicle systems. Current tests have failed to reproduce these severe, realistic conditions resulting in deficiencies in overall vehicle performance. In Phase I a prototype Brake Fade Advance Warning System (BFAWS) and mountain descent r ...

    SBIR Phase II 2017 Department of DefenseArmy
  8. Dense Arrays for High-Fidelity, Optically-Sampled Passive Millimeter-wave Imaging

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: A13040

    Under the proposed effort, PSI will continue to develop a novel pmmW imaging technology developed under a prior Navy program to realize dense form factor arrays. This technology is based on an optical upconverted distributed aperture technology that can make large effective apertures in low SWaP form factors thereby maximizing achievable resolution. This sensor technology has already reached TRL 6 ...

    SBIR Phase II 2017 Department of DefenseArmy
  9. Enhanced Cell Designs for Improved Internal Heat Transfer for High Rate and Power Capable, Large-Format Batteries

    SBC: K2 ENERGY SOLUTIONS, INC.            Topic: N151073

    A high energy density, high power cylindrical cell suitable for pulsed power operation with a capacity between 15 and 20 Ah will be developed. The cell will utilize a lithium iron phosphate chemistry and will utilize both internal and external thermal management technology to minimize temperature rise even under high power operation.

    SBIR Phase II 2017 Department of DefenseNavy
  10. Locality Scanner for Helicopter Pilotage and Hazard Avoidance

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: A15070

    Degraded visual environment (DVI) presents a challenge for helicopter pilotage, particularly in close proximity to potential hazards such as vegetation, poles, wires, buildings, vehicles, personnel, equipment, nearby terrain, other aircraft, or ship superstructures. To safely negotiate these hazards, the aircrew must maintain a continuous awareness of the environment that can include both static a ...

    SBIR Phase II 2017 Department of DefenseArmy
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