Award Data

City planners and engineers need detailed assessments of public rights-of-way to evaluate existing conditions, determine compliance with draft accessibility guidelines, and plan reconstruction projects. Current assessment methods are inadequate and inefficient due to the time and resources required. This project will develop an automated public rights-of-way assessment process and the measuremen ...

DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for new products/devices, tools, assays to improve our ability to precisely measure environmental exposure ...

DESCRIPTION (provided by applicant): Remarkable advances in signal processing techniques, materials sciences, battery technologies, and computer-aided design and computer-aided manufacturing (CAD/CAM) processes have led to significant developments in assistive technologies. Coordinated research and commercialization have dramatically increased prosthetic function, utility, personalization, comfort ...

DESCRIPTION (provided by applicant): Perchlorate, ClO4-, is a small highly water soluble anion created by both geogenic and anthropogenic sources. Anthropogenic sources include solid rocket fuel, matches, dyes, paints, airbag inflators, pyrotechnics, flares, and fertilizers. Human exposure to perchlorate is of concern because of the potential for impaired thyroid function, leading to a number of d ...

DESCRIPTION (provided by applicant): Tandem repeat sequences (STR) are distributed widely in the human genome. These sites exhibit high levels of length polymorphism as a result of their relative instability during DNA replication, i.e., the tendency for slippage to occur between the template and newly synthesized strands causing deletion or addition of repeat units. Changes in STR repeat numb ...

DESCRIPTION (provided by applicant): Since the introduction of liver transplantation, patient and graft outcomes have incrementally improved. Whole liver or segmental liver transplantation have been performed in patients suffering from different endstage liver diseases. The infusion of isolated hepatocytes has been investigated as an alternative to solid organ grafting. Transplantations of allogen ...

DESCRIPTION (provided by applicant): The goal of this project is to further develop novel bisphosphonate conjugate MBC-11 and other novel compounds as treatment for prostate cancer (PC) and PC-induced bone disease. MBC-11 is the anhydride formed between arabinocytidine (AraC)-59-phosphate and etidronate and is the lead product of our proprietary technology which employs conjugates of known chemoth ...

DESCRIPTION (provided by applicant): Statistical databases for public use pose a critical problem: how to make the data available for analysis without disclosing information that would infringe on privacy, violate confidentiality, or endanger national security. Organizations in the public and private sectors have a major stake in this confidentiality protection problem, given the fact that access ...

DESCRIPTION (provided by applicant): Preterm births are responsible for 75% of neonatal mortality and one-half of long-term neurological impairments in children as well as a substantial portion of all birth-related short- and long-term morbidity. In the United States, about 12.8 percent of babies (more than 500,000 per year) are born prematurely. The rate of premature birth has increased by 36 per ...

DESCRIPTION (provided by applicant): When responding to a chemical spill or other hazardous cleanup operation, first responders must frequently wear a level A hazardous materials suit. These suits protect the first responder from chemical exposure by completely sealing the wearer against external vapors and liquids. Because the suits are sealed, a fresh air supply is required which is typically pr ...