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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Public Rights-of-Way Assessment Instrumentation to Determine Accessibility

    SBC: BENEFICIAL DESIGNS INC            Topic: 081FH2

    City planners and engineers need detailed assessments of public rights-of-way to evaluate existing conditions, determine compliance with draft accessibility guidelines, and plan reconstruction projects. Current assessment methods are inadequate and inefficient due to the time and resources required. This project will develop an automated public rights-of-way assessment process and the measuremen ...

    SBIR Phase II 2010 Department of Transportation
  2. Treatment of Acute Coronary Syndromes with Recombinant LCAT Infusion

    SBC: ALPHACORE PHARMA, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The hallmark of atherosclerosis is the accumulation of cholesterol in arteries, resulting in plaque which can lead to a heart attack (myocardial infarction (MI)). The excess cholesterol causes inflammation, promotes plaque instability, and in later stages, narrows the vessel lumen to obstruct blood flow. Normally, cholesterol is removed from arteries and deli ...

    SBIR Phase II 2010 Department of Health and Human Services
  3. Phase II Environmentally greener, efficient, and safe synthetic platform for the

    SBC: BOROPHARM, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): We propose to continue expanding the study of iridium-catalyzed aromatic C-H activation/borylation in concert with other chemical conversions as a new approach to currently inaccessible chemical building blocks that will be highly useful for variety of practical applications, including pharmaceutical, agro-chemical, materials and fine chemical development. The ...

    SBIR Phase II 2010 Department of Health and Human Services
  4. S-nitrosothiol analyzer for the clinical diagnosis of cardiovascular disease mark

    SBC: ACCORD BIOMATERIALS, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The goal of this study is to develop a novel electrochemical S-nitrosothiol (RSNO) sensing system with an optimized detection limit and to finalize the specifications required to build a practical RSNO tool for clinical diagnostic applications. RSNO's are a primary carrier and reservoir of NO in vivo and are a potential pre-symptom marker for hypertensive disor ...

    SBIR Phase II 2010 Department of Health and Human Services
  5. A Systems Biology Platform for Integrative Cancer Biology Research

    SBC: GENEGO, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): A vast ocean of small experiments data and OMICs datasets is being accumulated in oncology research, and none of the currently available life sciences informatics platforms is capable of a comprehensive handling and meaningful functional analysis of these data. Here we propose to build such a system, MetaMiner (Oncology) on the base of our mature data analysi ...

    SBIR Phase II 2010 Department of Health and Human Services
  6. Enhanced Propagation of Adult Human Renal Epithelial Cells Allowing for Commercia

    SBC: Innovative Biotherapies, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Renal cell therapy promises to improve the survival and overall health of patients suffering from acute renal failure (ARF), acute tubular necrosis (ATN), multiple organ failure (MOF), sepsis, cardiorenal syndrome (CRS) and end stage renal disease (ESRD). To this end, therapeutic biological devices addressing the neglected physiologic component of renal replace ...

    SBIR Phase II 2010 Department of Health and Human Services
  7. Field-Based Gait Monitoring System for the Elderly

    SBC: INTELLIGENT PROSTHETIC SYSTEMS, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Health management of older adults can be improved through convenient and objective assessment of their gait. Although a number of quantitative measures of walking, such as the variability of steps taken, have been shown to predict the risk of falls, these measurements are difficult to obtain outside the laboratory. It would be helpful to obtain accurate and ob ...

    SBIR Phase II 2010 Department of Health and Human Services
  8. Geostatistical software for the analysis of individual-level epidemiologic data

    SBC: BIO-ANALYTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR project is developing the first geostatistical software to offer tools that are specifically designed for the geostatistical analysis of both aggregated and individual-level health data, providing: (1) the description of spatial patterns of cancer incidence and mortality rates and identification of nested scales of variation; (2) the spatial interpola ...

    SBIR Phase II 2009 Department of Health and Human Services
  9. Case-only Cancer Clustering for Mobile Populations

    SBC: BIO-ANALYTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will develop new approaches for evaluating cancer clusters using case-only data. To date three major deficiencies of studies of space-time clustering are that they assume the place-of-residence at time of observation (e.g. diagnosis or death) is representative of place-based exposures over the life course; do not routinely assess the sensitivity of ...

    SBIR Phase II 2009 Department of Health and Human Services
  10. Extended Thermodynamic Database for Modified Oligonucleotides

    SBC: DNA SOFTWARE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A greatly expanded thermodynamic database for modified oligonucleotides will be developed in this project and incorporated into existing design software. This Fast Track SBIR proposal focuses on determining thermodynamic parameters for modifications that are currently finding widespread applications. The new thermodynamic database and software will enable a lar ...

    SBIR Phase II 2009 Department of Health and Human Services
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