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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a Yellow Fever Vaccine for a Vulnerable Population

    SBC: NAJIT TECHNOLOGIES, INC.            Topic: NIAID

    ABSTRACT Yellow fever virusYFVrepresents a mosquito borne emerging re emerging human pathogen that causesmortality and is endemic in andgtcountriesThe current live attenuated YFV vaccine was developed inand following the establishment of a virus seed lot systemit has not been modified or otherwise improved in overyearsAccording to the CDCthis vaccine causesserious adverse eventsSAEper million vacc ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. A Novel Glycosaminoglycan-Based Therapeutic for Chronic Rhinosinusitis

    SBC: GLYCOMIRA, LLC            Topic: NIAID

    PROJECT SUMMARY Chronic rhinosinusitisCRSis one of the most prevalent inflammatory diseases in the U Saffecting up toof the population and substantially diminishing the quality of life and productivity of patientsIn four yearsthe annual U Shealth care expenditure to treat patients with CRS dramatically increased from $ B to $Bof the health care budgetwith a corresponding rise in surgical treatment ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. InGaAs Focal-plane Arrays for Coherent Ladar

    SBC: VOXTEL, INC.            Topic: AF171129

    Voxtel proposes to develop, characterize, and demonstrate a coherent-ladar optimized readout integrated circuit (ROIC) consisting of 40-micron pixel elements, including circuits designed for snapshot-integration operation as short as 250 ns, formatted in a 32 x 32 array capable of readout speeds of 1 M frames per second. In Phase I, the coherent ladar ROIC architecture was developed and specificat ...

    SBIR Phase II 2018 Department of DefenseAir Force
  4. Adversarial Detection, Inference & Defensive Response (ADIDRUS)

    SBC: Galois, Inc.            Topic: OSD11IA2

    Insider threat poses one of the most problematic cyber challenges facing the warfighter today. This threat to Air Force assets is particularly insidiousas trusted individuals have easy access to sensitive and classified information. Galois, Inc. has developed a multi-layered attack inference engine called ADIDRUS, originally designed to help UAVs fight through cyber attacks. ADIDRUS continuously m ...

    SBIR Phase II 2018 Department of DefenseAir Force
  5. Protect Yourself! Abuse Prevention for People with Intellectual Disabilities

    SBC: DOUBLE S INSTRUCTIONAL SYSTEMS            Topic: NICHD

    PROJECT SUMMARYIndividuals with intellectual disabilitiesIDare at higher risk for abuse than the general populationIncreasing numbers of people with ID are living independently in the community with both its benefits and its risksMany individuals with ID are subjected to physicalsexualand verbal abuseSome of the characteristics found in people with IDshort attention spandifficulties with abstract ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    Project Summary Metabolic reprogramming plays a critical role in carcinogenesisin part due its ability to promote immune suppressive properties within tumorsHoweverit is unclear whether inhibition of fatty acid metabolism in tumors affects their immunogenicityHerewe show for the first time that inhibition of stearoyl CoA desaturaseSCDthe rate limiting enzyme involved in fatty acid synthesis conver ...

    STTR Phase II 2018 Department of Health and Human Services
  7. Development of PEGylated MTI-101 for the treatment of relapsed Myeloma

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    ABSTRACTModulation Therapeutics is developing a first in class cyclic peptide coined MTIfor the treatment of multiple myelomaThe company currently has a license for the parent molecule which has been awarded a patent covering the intellectual property for both composition of matter and use in cancer in the US and EuropeModulation Therapeutics is now poised to further advance this class of compound ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. NIIRS 9 Small Unmanned Aircraft System (SUAS) 5-Inch Gimbal

    SBC: TRILLIUM ENGINEERING LLC            Topic: AF171119

    Phase I focused on the selection of a camera and associated optics that would deliver the required imagery along with a concept of operation (CONOP) for the system. Though Phase I isnt complete, preliminary results strongly support the use of a small, zoomable full motion video (FMV) camera for target acquisition paired with an 18MP camera and custom 250mm catadioptric lens to capture still images ...

    SBIR Phase II 2018 Department of DefenseAir Force
  9. Wafer-Level Electronic-Photonic Co-Packaging

    SBC: Phase Sensitive Innovations, Inc.            Topic: AF16AT01

    In phase II work, we will collaborate with Prof. Stefan Preble in RIT and continue to develop large scale hybrid integration and packaging techniques for key active photonic components such as lithium niobate on insulator (LNOI) modulators and modified uni-traveling (MUTC) photodiodes. We will demonstrate a low V, broadband, small footprint LNOI modulator with hybrid Si/LN or SiN/LN waveguide usin ...

    STTR Phase II 2018 Department of DefenseAir Force
  10. High-gain Low-excess-noise Linear-mode APD for Small-pitch Ladar

    SBC: VOXTEL, INC.            Topic: AF171118

    A high-sensitivity, narrow-field-of-view ladar receiver, optimized for long-range target detection and identification will be developed, characterized, and demonstrated.In Phase I avalanche photodetector (APD) and readout integrated circuit (ROIC) components were tested and validated. In Phase II, the pulse amplification, detection, and timing circuitry will be cast as a fine-pitch 1616-format arr ...

    SBIR Phase II 2018 Department of DefenseAir Force

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