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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Detect, Locate, and Mitigate GPS Threats

    SBC: QUNAV LLC            Topic: A17119

    Phase I effort will develop an innovative Exploitation of Discrete GPS interference for Enhanced navigation (EDGE) technology. EDGE uses existing antenna configurations and RF front-ends on a missile platform (or similar platforms) to detect and locate GPS interferers (jammers and spoofers). Localized interference sources are then exploited for navigation, targeting, and guidance. Common approache ...

    SBIR Phase I 2018 Department of DefenseArmy
  2. Bone Conduction Audio & Vibrotactile Transducer for Dual-Use Communication

    SBC: Engineering Acoustics Incorporated            Topic: A16019

    Tactical situation awareness (SA) is critical for ensuring the Warfighters situational dominance, especially during combat. SA can improve security, survivability and optimize lethality. The object of this SBIR is to develop a dual-mode transducer (B-Tac) that provides both bone conduction (BC) sound transmission and vibrotactile cues. The merit of each technology alone has been shown to enhance p ...

    SBIR Phase II 2018 Department of DefenseArmy
  3. Capacitive removal of PFOA and PFOS from Drinking Water

    SBC: MAINSTREAM ENGINEERING CORP            Topic: 17NCER1A

    Polyfluoroalkyl and perfluoroalkyl compounds (PFCs) have been used commercially since the 1940’s due to their high level of chemical stability, almost frictionless surface or waterproofing characteristics. Elevated levels of PFCs have been linked to cancer and other health problems including reproductive and developmental risks. PFOA and PFOS are amongst the most prevalent of the PFCs with low l ...

    SBIR Phase I 2018 Environmental Protection Agency
  4. A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector

    SBC: FRAMERGY INC            Topic: 17NCER2C

    To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...

    SBIR Phase I 2018 Environmental Protection Agency
  5. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: CAREVIVE SYSTEMS INC            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Topic 373: Exonuclease Time-of-Flight for the Low-Cost, Rapid Identification of Methylated RNA Single Molecules

    SBC: Digital Nanogenetics LLC            Topic: NCI

    There is growing interest in the study of RNA modifications and its potential role(s) in many physiological abnormalities, such as modulating many processes associated with cancer development and progression. While RNA sequencing (RNA-seq) using short-read nextgeneration sequencing (NGS) have proven to be a useful tool for identifying specific RNA modifications, there still remains technical chall ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. TFEB Activator for Alzheimer's Disease Therapy

    SBC: BRILLIANT BIOSCIENCES INC.            Topic: NIA

    One in ten of the persons ageare affected by Alzheimer s diseaseADcausing enormous social and economic burden to the United StatesTo date only five medications have been approved by the FDA for the treatment of the symptoms of ADbut none of them slows or stops the disease progressionWith the recent repeated failures of AD drugs on thesecretase inhibitorsthe need for an effective AD drug became eve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells

    SBC: ISOPLEXIS CORPORATION            Topic: 172

    SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Device for Rapid, Complete & Durable Occlusion of Wide-Neck Cerebral Aneurysms

    SBC: Artio Medical, Inc            Topic: 106

    ABSTRACT Metactive Medical is developing the Ballstent Microcatheteran innovative medical device for the endovascular embolic treatment of cerebral aneurysmswhich are a common cause of strokeThe key component of the device is the Ballstentan expandabledetachablegold metal balloon that can be pleated and folded at the distal end of a delivery microcatheteradvanced into an aneurysm sac over a guidew ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Cpf1-mediated inactivation of an AAV transgene

    SBC: EMMUNE INC            Topic: NIAID

    PROJECT SUMMARY The Farzan laboratory has developed what appears to be an effective way to prevent HIVinfectionThis approach combines eCDIgan exceptionally broad and potent HIVentry inhibitorwith an adenoassociated virusAAVdelivery systemFor more than a year after a one time intramuscular inoculation with AAV eCDIgrhesus macaques were protected against multiple high dose intravenous challenges wit ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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