Award Data

The Digital Greenhouse concept is to work with users from operational organizations in off-site commercial locations, positioned near Air Force logistics centers, to quickly develop “user storiesâ€Â for use in rapid development of working prototypes. These prototypes will be tested and validated by these users for use in application modernization projects capable of providing advanced ...

Per- and polyflouralkyl substances, otherwise known as PFAS, are a large group of chemicals including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). These chemicals have a large variety of uses globally. Remediation of PFAS has gained importance due to their environmental persistence and toxicity. Water treatment methods must combine multiple strategies to be effective, as PF ...

To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logisticalsystem requires natural gas gathering lines, processing facilities,product storage tanks and Jots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermitte ...

This project develops and tests a Bluetooth compliant tongue-based electronic controller (a.k.a. “Mouth Mouse”), designed to give people with upper limb disability control of peripheral devices including computers and communication systems, home automation, and powered wheelchairs, as well as many other Bluetooth compliant devices and new technologies to come in the future. The Mouth Mouse is ...

TuberculosisTBkilled an estimatedmillion people in the world inOverof the mortalities associated with this deisease occurred in regions of the world where access to reliable TB testing and other suppotive infrastructure is severely limitedUntil there are pivotal technological innovations in the diagnosis of TB for point of carePOCapplicationthe ambitious goals of the WHO s End TB strategyareductio ...

The Contractorwill use modern technology to develop a fully integratedcommercially viable device for controlled pharmaceutical drug detectiondeactivationand disposal to ensure compliance with DEA regulations and deter opioid theft

ABSTRACT Stroke is the fifth leading cause of death and the leading cause of disability in the United StatesThere remains a critical need for innovative therapeutic approaches that can successfully prevent or reverse brain injury following strokeDysfunction of the mitochondrial biochemistry following ischemic stroke and reperfusion injury contributes to significant neuronal cell losshoweverthe dev ...

ABSTRACT Despite the overefficacy of diabetic retinopathyDRtreatmentit continues to be the leading cause of blindness in working age AmericansOvermillion adults in the US have diabetesOf thesewill develop DR andwill develop vision threatening DRVTDRCurrentlyless than half of all patients with diabetes receive the recommended annual dilated eye exam andof those diagnosed with VTDRonlyundergo timely ...

Project Summary Abstract Currently available anti thymocyte globulinATGproducts are polyclonal animal antibodiesATGAMequine polyclonal ATGThymoglobulinrabbit polyclonal ATGand have found broad use as immune tolerizing agentsparticularly for induction therapy in a majority of tissue transplantsfor acute transplant rejectionand as treatment for graft vshost disease following bone marrow transplantsE ...

While CAR-T therapies have advanced in the clinic, there are still two specific issues using these breakthrough therapies for blood cancers: Durable responses in patients are only at 30-50% and Cytokine Release Syndrome occurs in 60-90% of treated patients. These limitations, for a drug that costs as much as $500,000, may cost an additional $250,000+ for treating adverse events leading to caution ...