Award Data

Modern DoD applications are benefiting from the proliferation of EO/IR sensor technology. As imagers become cheaper and smaller, they are being more widely deployed for a variety of scenarios. This trend is exemplified by the Navys Future Targeting System (FTS), which will provide laser designation, laser spot imaging, and some target location functions in a single 5.5-pound unit, replacing discre ...

The primary objective of this Phase I proposal is to design, develop, and demonstrate the feasibility of a power factor compensation device for a 65 kVA, 115V, 400-Hz aircraft power system. Based on identified power factor conditions in the F-18 Super Hornet platform, the compensation system must correct an existing leading 0.98 power factor to a target lagging 0.93 (minimum objective lagging 0.97 ...

To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...

SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...

Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

PROJECT SUMMARY Chronic rhinosinusitis (CRS) is one of the most prevalent inflammatory diseases in the U.S., affecting up to 16% of the population and substantially diminishing the quality of life and productivity of patients. In four years, the annual U.S. health care expenditure to treat patients with CRS dramatically increased from $9B to $64B (5% of the health care budget), with a correspondin ...

Summary Enhanced Recovery of Pharmaceutical Solvent driven by EPA InitiativeThe United States Environmental Protection AgencyEPAis establishing new safeguards for hazardous secondary materials with objectives to promote the economicenvironmentaland public health benefits of recycling wasteswith an emphasis on several industrial sectorsincluding the pharmaceutical industryOn averagepharmaceutical m ...

Global epidemics of obesity and its associated comorbidities pose formidable challenges to human healthCurrent few medications available for obesity treatment only produce modest effects and are usually accompanied with unpleasantpotentially harmful side effectsThere is accumulating evidence that significant metabolic differences that distinguish beige brown adipocytes from white adipocytes can po ...

Abstract This application, “Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein- protein interaction,” addresses the critical need for more effective medications to treat chronic neuropathic pain affecting ~116 million people in the United States. Current pain medications such as NSAIDS, steroids, opiates and gabapentin analogs have documented and often severe sid ...

The number of decayed and filled tooth surfaces in primary dentition is on the rise in US children between the ages ofandyears oldin factof adolescentsbetweenandyears oldandout ofdentate seniorsagebear evidence of dental cariesReinforced with areport statingof those between the ages ofandhave dental cariesvirtually all walks of life are thus affectedand this doesn t even include those unreportedor ...