Award Data

SpaceWorks proposes to continue development and advancement of its novel QuickShot trajectory optimization software suite. A number of new modeling capabilities of value when simulating advanced military systems will be implemented. Additionally, a variety of case studies and applications that will showcase and demonstrate utilization of these new features will be conducted.

Per- and polyflouralkyl substances, otherwise known as PFAS, are a large group of chemicals including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). These chemicals have a large variety of uses globally. Remediation of PFAS has gained importance due to their environmental persistence and toxicity. Water treatment methods must combine multiple strategies to be effective, as PF ...

To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logisticalsystem requires natural gas gathering lines, processing facilities,product storage tanks and Jots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermitte ...

TuberculosisTBkilled an estimatedmillion people in the world inOverof the mortalities associated with this deisease occurred in regions of the world where access to reliable TB testing and other suppotive infrastructure is severely limitedUntil there are pivotal technological innovations in the diagnosis of TB for point of carePOCapplicationthe ambitious goals of the WHO s End TB strategyareductio ...

lnterleukinILand granulocyte macrophage colony stimulating factorGM CSFare endogenous immune activatorsEarlier studies using soluble ILand GM CSF as vaccine adjuvants were unsuccessful due to toxicity or suboptimal responseWe developed versions of ILand GM CSF with a glycosylated phosphatidylinositolGPIanchor added at the carboxyl terminusallowing incorporation into lipid bilayers such as in influ ...

Tuberculosis is a persistent infectious disease that threatens the health of people and numerous mammalian species throughout the worldMonitoring of Mycobacterium tuberculosisMtbinfections in animal models has often relied on host mortalitybacterial loadsand qualitative assessment of pathology at necropsyThese are blunt toolslargely unrelated to the markers used for diagnosis and epidemiological s ...

The Contractorwill use modern technology to develop a fully integratedcommercially viable device for controlled pharmaceutical drug detectiondeactivationand disposal to ensure compliance with DEA regulations and deter opioid theft

ABSTRACT Stroke is the fifth leading cause of death and the leading cause of disability in the United StatesThere remains a critical need for innovative therapeutic approaches that can successfully prevent or reverse brain injury following strokeDysfunction of the mitochondrial biochemistry following ischemic stroke and reperfusion injury contributes to significant neuronal cell losshoweverthe dev ...

AbstractNorovirus is the most common cause of acute gastroenteritis in the United States, associated annually with 19-21 million illnesses, 56,000-71,000 hospitalizations and 570-800 deaths (US CDC, Overview about Norovirus). Norovirus is one of the nonenveloped viruses that are resistant to alcohol sanitization. According to US CDC Guidelines for the Prevention and Control of Norovirus Gastroente ...

PROJECT SUMMARY ABSTRACT Recent advances in clinical gene therapy highlight the need for improved lentiviral vectorLVand adenoassociated viralAAVvector manufacture and utilization efficiencies for enhanced therapeutics outcomesExpression Therapeutics in collaboration with Emory University are developing a microfluidicFluidictechnology based solution that overcomes the mass transport and diffusion ...