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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector
SBC: FRAMERGY INC Topic: 17NCER2CTo reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...
SBIR Phase I 2018 Environmental Protection Agency -
Topic 375: 18F PET Tracer For Imaging PD-L1 (Moonshot)
SBC: SIBTECH, INC. Topic: NCINew therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Method to Increase Buprenorphine Treatment Capacity and Effectiveness
SBC: CBT4CBT LLC Topic: R42The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioiddependent patientsOvermillion people in the US are addicted to opiatesProviding effective agonist therapymethadone or buprenorphinecoupled with behavioral counseling greatly improves outcomesreduces morbidityand reduces societal costsMethadone maintenance treatment has been limited due to complex sta ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of an Oral Acidic Mammalian Chitinase Inhibitor to Treat Asthma
SBC: ONCOARENDI THERAPEUTICS LLC Topic: NHLBIApproximatelymillion Americans suffer from asthmawhich leads to aboutdeaths per yearand is responsible for estimated annual total direct and indirect costs of $billionDespite the existing treatments for asthmapredominantly combinations of inhaledagonists and corticosteroidsCSsthere remains a significant unmet medical need for new therapies which address two key issuesapproximatelyof patients are i ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Deep Learning to Transform Clinician Autism Diagnostic Assessments and More
SBC: Caring Technologies Inc. Topic: 103NODA Telehealth system improves access to an autism diagnostic assessment by guiding families to share video clips of their child at homeso diagnostic clinicians can directly observe andtagvideo of any atypical behaviorand if warrantedrender a diagnosisThis system is evidence based and has been commercializedwith several published studies to discuss the benefitsWe now propose to improve this servi ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
An antigen-detection assay to diagnose Babesia microti infection
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDProject Summary Human babesiosis is a malaria like multisystem disease caused primarily by Babesia microtian emerging apicomplexan parasite that infects and develops within human erythrocytesThe parasite is transmitted to humans by the tick vector Ixodes scapularis and can also be introduced through blood transfusionInfection can cause flu like symptomsand severe infection can be fatalin particula ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells
SBC: ISOPLEXIS CORPORATION Topic: 172SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a hybrid transcatheter mitral valve replacement and repair device
SBC: Dura LLC Topic: NHLBIPROJECT SUMMARYMitral regurgitationMRis the most prevalent valvular heart disease in the U Saffecting approximatelyof the populationThere aremillion patients in the US with moderate to severe MR requiring treatmentHoweveronly approximatelypatients in the U Sundergo surgery for MR each year due to concerns about procedural complexity and patient safetyThere is great enthusiasm among the heart valve ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Bioengineered skin microbiota for cutaneous mitigation of Netherton Syndrome
SBC: Azitra Inc. Topic: NIAMSPROJECT SUMMARY Current treatment options for many skin diseases especially rare diseases fail to address the underlying causative pathophysiologiesIn the case of genetic mutations that cause loss of function mutationssupplementing the missing protein is a viable approach to treatmentHoweverdelivery of functional protein to the target keratinocytes presents a significant challengemoreoverthe cost ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Glycosaminoglycan-Based Therapeutic for Chronic Rhinosinusitis
SBC: GLYCOMIRA, LLC Topic: NIAIDPROJECT SUMMARY Chronic rhinosinusitis (CRS) is one of the most prevalent inflammatory diseases in the U.S., affecting up to 16% of the population and substantially diminishing the quality of life and productivity of patients. In four years, the annual U.S. health care expenditure to treat patients with CRS dramatically increased from $9B to $64B (5% of the health care budget), with a correspondin ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health